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10.4161/15384047.2014.955442 http://scihub22266oqcxt.onion/10.4161/15384047.2014.955442 C4622859!4622859!25482951     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Cancer+Biol+Ther 2014 ; 15 (11): 1444-55 Nephropedia Template TP {{tp|p=25482951|t=2014. miRNA biogenesis: Biological impact in the development of cancer |pdf=|usr=}}{{25482951}} gab.com Text miRNA biogenesis: Biological impact in the development of cancer JO: Cancer Biol Ther http://www.kidney.de/pget.php?&tw=1&pmid=25482951 #FOAvip microRNAs (miRNAs) are non coding RNAs with different biological functions and pathological implications. Given their role as post-transcriptional gene expression regulators, they are involved in several important physiological processes like development, cell differentiation and cell signaling. miRNAs act as modulators of gene expression programs in different diseases, particularly in cancer, where they act through the repression of genes which are critical for carcinogenesis. The expression level of mature miRNAs is the result of a fine mechanism of biogenesis, carried out by different enzymatic complexes that exert their function at transcriptional and post-transcriptional levels. In this review, we will focus our discussion on the alterations in the miRNA biogenesis machinery, and its impact on the establishment and development of cancer programs. Twit Text FOAVip miRNA biogenesis: Biological impact in the development of cancer ????Cancer Biol Ther http://www.kidney.de/pget.php?&tw=1&pmid=25482951 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25482951 #FOAvip English Wikipedia <ref>{{Cite pmid|25482951}}</ref> miRNA biogenesis: Biological impact in the development of cancer #MMPMID25482951 Romero-Cordoba SL; Salido-Guadarrama I; Rodriguez-Dorantes M; Hidalgo-Miranda A Cancer Biol Ther 2014[Nov]; 15 (11): 1444-55 PMID25482951show ga microRNAs (miRNAs) are non coding RNAs with different biological functions and pathological implications. Given their role as post-transcriptional gene expression regulators, they are involved in several important physiological processes like development, cell differentiation and cell signaling. miRNAs act as modulators of gene expression programs in different diseases, particularly in cancer, where they act through the repression of genes which are critical for carcinogenesis. The expression level of mature miRNAs is the result of a fine mechanism of biogenesis, carried out by different enzymatic complexes that exert their function at transcriptional and post-transcriptional levels. In this review, we will focus our discussion on the alterations in the miRNA biogenesis machinery, and its impact on the establishment and development of cancer programs. ämiRNA biogenesis: Biological impact in the development of cancer (epmc).pdf DeepDyve Pubget Overpricing