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.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 Medicine+(Baltimore)
2015 ; 94
(36
): e1482
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Different Risk of Common Gastrointestinal Disease Between Groups Undergoing
Hemodialysis or Peritoneal Dialysis or With Non-End Stage Renal Disease: A
Nationwide Population-Based Cohort Study
#MMPMID26356710
Lee YC
; Hung SY
; Wang HH
; Wang HK
; Lin CW
; Chang MY
; Ho LC
; Chen YT
; Wu CF
; Chen HC
; Wang WM
; Sung JM
; Chiou YY
; Lin SH
Medicine (Baltimore)
2015[Sep]; 94
(36
): e1482
PMID26356710
show ga
Peritoneal dialysis (PD) is one type of renal replacement therapy, but potential
peritoneal damage and gastrointestinal (GI) tract adverse effects during
long-term exposure to bio-incompatible dialysate remain a concern. Although GI
disease frequently occurs in dialysis patients, whether the risk of GI diseases
differs among PD and hemodialysis (HD) or non-uremic groups is still uncertain.In
this retrospective cohort study, data were obtained from the National Health
Insurance Research Database, which includes almost all dialysis patients in
Taiwan. Between 2000 and 2009, a total of 1791 PD and 8955 HD incident patients
were enrolled and matched for age and sex or for propensity score. In addition, a
comparison cohort of 8955 non-uremic patients was also selected. Individuals were
monitored for the occurrence of common GI diseases until 2010, and data were
analyzed using several different models.Generally speaking, the results showed
that the risk of gastroesophageal reflux, intestinal obstruction or adhesions,
and abdominal hernia was significantly higher in the PD group, whereas the risk
of peptic ulcer disease and lower GI diverticula and bleeding was significantly
greater in the HD group. Meanwhile, the risk of mesenteric ischemia, liver
cirrhosis, and acute pancreatitis was higher in dialysis patients, but was not
significantly different between the PD and HD groups; moreover, the risk of
appendicitis in the PD group appeared to be lower than that in the HD group.In
conclusion, dialysis patients have a higher risk of most common GI diseases, and
PD and HD modalities are associated with different GI diseases.