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10.1097/MD.0000000000000901 http://scihub22266oqcxt.onion/10.1097/MD.0000000000000901 C4616483!4616483 !26061310     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=26061310 &cmd=llinks): Failed to open stream: HTTP request failed! 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Serum Alpha-Fetoprotein Has High Specificity for the Early Detection of Hepatocellular Carcinoma After Hepatitis C Virus Eradication in Patients |pdf=|usr=}}{{26061310 }} gab.com Text Serum Alpha-Fetoprotein Has High Specificity for the Early Detection of Hepatocellular Carcinoma After Hepatitis C Virus Eradication in Patients JO: Medicine (Baltimore) http://www.kidney.de/pget.php?&tw=1&pmid=26061310 #FOAvip Alpha-fetoprotein (AFP) has not played a large role in the surveillance of hepatocellular carcinoma due to inadequate sensitivity and specificity for active chronic hepatitis or cirrhosis. The aim of this study was to evaluate the diagnostic accuracy of AFP in small hepatocellular carcinomas after hepatitis C virus eradication to determine the optimal cutoff value. We conducted a case-control study of 29 cases and 58 controls, matched for age, gender, and platelet counts. The AFP cutoff was 5?ng/mL in patients after hepatitis C virus eradication and 17?ng/mL in those without hepatitis C virus eradication. The areas under the receiver operating characteristic curve were 0.86 (95% confidence interval, 0.76-0.96) in patients after hepatitis C virus eradication and 0.83 (95% confidence interval, 0.74-0.91) in those without hepatitis C virus eradication. In patients after hepatitis C virus eradication, the sensitivity and specificity of AFP levels were 24.1% and 100%, respectively, using a cutoff value of 17?ng/mL. Using a lower cutoff value of 5?ng/mL, the sensitivity increased to 75.9%, although the specificity decreased to 89.0%. AFP is a specific tumor marker for the diagnosis of hepatocellular carcinoma after hepatitis C virus eradication when using the optimal cutoff value of 5?ng/mL. Twit Text FOAVip Serum Alpha-Fetoprotein Has High Specificity for the Early Detection of Hepatocellular Carcinoma After Hepatitis C Virus Eradication in Patients ????Medicine (Baltimore) http://www.kidney.de/pget.php?&tw=1&pmid=26061310 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26061310 #FOAvip English Wikipedia <ref>{{Cite pmid|26061310 }}</ref> Serum Alpha-Fetoprotein Has High Specificity for the Early Detection of Hepatocellular Carcinoma After Hepatitis C Virus Eradication in Patients #MMPMID26061310 Minami T ; Tateishi R ; Kondo M ; Nakagomi R ; Fujiwara N ; Sato M ; Uchino K ; Enooku K ; Nakagawa H ; Asaoka Y ; Kondo Y ; Moriya K ; Shiina S ; Koike K Medicine (Baltimore) 2015[Jun]; 94 (23 ): e901 PMID26061310 show ga Alpha-fetoprotein (AFP) has not played a large role in the surveillance of hepatocellular carcinoma due to inadequate sensitivity and specificity for active chronic hepatitis or cirrhosis. The aim of this study was to evaluate the diagnostic accuracy of AFP in small hepatocellular carcinomas after hepatitis C virus eradication to determine the optimal cutoff value. We conducted a case-control study of 29 cases and 58 controls, matched for age, gender, and platelet counts. The AFP cutoff was 5?ng/mL in patients after hepatitis C virus eradication and 17?ng/mL in those without hepatitis C virus eradication. The areas under the receiver operating characteristic curve were 0.86 (95% confidence interval, 0.76-0.96) in patients after hepatitis C virus eradication and 0.83 (95% confidence interval, 0.74-0.91) in those without hepatitis C virus eradication. In patients after hepatitis C virus eradication, the sensitivity and specificity of AFP levels were 24.1% and 100%, respectively, using a cutoff value of 17?ng/mL. Using a lower cutoff value of 5?ng/mL, the sensitivity increased to 75.9%, although the specificity decreased to 89.0%. AFP is a specific tumor marker for the diagnosis of hepatocellular carcinoma after hepatitis C virus eradication when using the optimal cutoff value of 5?ng/mL. |Aged [MESH] |Carcinoma, Hepatocellular/*blood/etiology [MESH] |Case-Control Studies [MESH] |Early Detection of Cancer/*methods [MESH] |Female [MESH] |Hepacivirus [MESH] |Hepatitis C, Chronic/complications/drug therapy [MESH] |Humans [MESH] |Liver Neoplasms/*blood/etiology [MESH] |Male [MESH] |Middle Aged [MESH] |Remission Induction [MESH] |Retrospective Studies [MESH] |Sensitivity and Specificity [MESH]Serum Alpha-Fetoprotein Has High Specificity for the Early Detection o(epmc).pdf DeepDyve Pubget Overpricing