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10.1097/MD.0000000000000087 http://scihub22266oqcxt.onion/10.1097/MD.0000000000000087 C4616289!4616289 !25275527     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=25275527 &cmd=llinks): Failed to open stream: HTTP request failed! 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Comparison of the interferon-gamma release assay with the traditional methods for detecting Mycobacterium tuberculosis infection in children |pdf=|usr=}}{{25275527 }} gab.com Text Comparison of the interferon-gamma release assay with the traditional methods for detecting Mycobacterium tuberculosis infection in children JO: Medicine (Baltimore) http://www.kidney.de/pget.php?&tw=1&pmid=25275527 #FOAvip The purpose of the article is to compare the whole blood interferon-? release assay (IGRA) with the traditional methods for detecting Mycobacterium tuberculosis (MTB) infection in children. Fifteen childhood patients with tuberculosis and 15 healthy children were recruited. Sputa samples and venous blood were collected, and according to different procedures, IGRA, sputum smear, colloidal gold assay (CGA), fluorescence quantitation polymerase chain reaction (FQ-PCR), and tuberculosis skin test (TST) were, respectively, performed. Thirty healthy children vaccinated with Bacillus Calmette-Guérin (BCG) were also recruited, and the comparative test was carried out between IGRA and TST. In all of 15 childhood patients with TB, the positive rates were 86.7%, 20.0%, 26.7%, 40%, and 66.7% in IGRA, sputum smear, CGA, FQ-PCR, and TST, respectively. In the children vaccinated with BCG, the positive rate of IGRA was significantly lower than that of TST (6.7% vs 76.7%). From high to low, the specificities of the five methods were sputum smear (100%), IGRA (86.7%), FQ-PCR (86.7%), TST (40%), and CGA (26.7%). Although the specificities of sputum smear and FQ-PCR were more than or equal to that of IGRA, the relative sensitivities limited their applications in populations of children. IGRA is a sensitive and specific method, and could be taken as a first choice for detecting MTB infection in populations of children. Twit Text FOAVip Comparison of the interferon-gamma release assay with the traditional methods for detecting Mycobacterium tuberculosis infection in children ????Medicine (Baltimore) http://www.kidney.de/pget.php?&tw=1&pmid=25275527 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25275527 #FOAvip English Wikipedia <ref>{{Cite pmid|25275527 }}</ref> Comparison of the interferon-gamma release assay with the traditional methods for detecting Mycobacterium tuberculosis infection in children #MMPMID25275527 Zhou J ; Kong C ; Shi Y ; Zhang Z ; Yuan Z Medicine (Baltimore) 2014[Oct]; 93 (15 ): e87 PMID25275527 show ga The purpose of the article is to compare the whole blood interferon-? release assay (IGRA) with the traditional methods for detecting Mycobacterium tuberculosis (MTB) infection in children. Fifteen childhood patients with tuberculosis and 15 healthy children were recruited. Sputa samples and venous blood were collected, and according to different procedures, IGRA, sputum smear, colloidal gold assay (CGA), fluorescence quantitation polymerase chain reaction (FQ-PCR), and tuberculosis skin test (TST) were, respectively, performed. Thirty healthy children vaccinated with Bacillus Calmette-Guérin (BCG) were also recruited, and the comparative test was carried out between IGRA and TST. In all of 15 childhood patients with TB, the positive rates were 86.7%, 20.0%, 26.7%, 40%, and 66.7% in IGRA, sputum smear, CGA, FQ-PCR, and TST, respectively. In the children vaccinated with BCG, the positive rate of IGRA was significantly lower than that of TST (6.7% vs 76.7%). From high to low, the specificities of the five methods were sputum smear (100%), IGRA (86.7%), FQ-PCR (86.7%), TST (40%), and CGA (26.7%). Although the specificities of sputum smear and FQ-PCR were more than or equal to that of IGRA, the relative sensitivities limited their applications in populations of children. IGRA is a sensitive and specific method, and could be taken as a first choice for detecting MTB infection in populations of children. |*Interferon-gamma Release Tests [MESH] |Adolescent [MESH] |BCG Vaccine [MESH] |Child [MESH] |Child, Preschool [MESH] |Female [MESH] |Gold Colloid [MESH] |Humans [MESH] |Male [MESH] |Polymerase Chain Reaction [MESH] |Sensitivity and Specificity [MESH] |Tuberculin Test [MESH] |Tuberculosis/*diagnosis [MESH]Comparison of the interferon-gamma release assay with the traditional (epmc).pdf DeepDyve Pubget Overpricing