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10.4161/19490976.2014.972238

http://scihub22266oqcxt.onion/10.4161/19490976.2014.972238
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C4615892!4615892!25483327
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suck abstract from ncbi


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pmid25483327      Gut+Microbes 2014 ; 5 (6): 761-5
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  • Antimicrobial peptides and the enteric mucus layer act in concert to protect the intestinal mucosa #MMPMID25483327
  • Dupont A; Heinbockel L; Brandenburg K; Hornef MW
  • Gut Microbes 2014[]; 5 (6): 761-5 PMID25483327show ga
  • The intestinal mucosa squares the circle by allowing efficient nutrient absorption while generating a firm barrier toward the enteric microbiota, enteropathogenic microorganisms and high luminal concentrations of potent immunostimulatory molecules. The mucus layer together with local antimicrobial and anti-inflammatory peptides significantly contribute to this ability. Here we summarize the recent progress made to better understand the critical importance of this dynamic, complex and highly structured anti-inflammatory and antimicrobial barrier.
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