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10.4161/19491034.2014.990858 http://scihub22266oqcxt.onion/10.4161/19491034.2014.990858 C4615675!4615675!25495074     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Nucleus 2014 ; 5 (6): 493-8 Nephropedia Template TP {{tp|p=25495074|t=2014. Nucleolus Precursor Body (NPB): A Distinct Structure in Mammalian Oocytes and Zygotes |pdf=|usr=}}{{25495074}} gab.com Text Nucleolus Precursor Body (NPB): A Distinct Structure in Mammalian Oocytes and Zygotes JO: Nucleus http://www.kidney.de/pget.php?&tw=1&pmid=25495074 #FOAvip Nucleoli in mammalian oocytes and zygotes, sometimes referred to as nucleolus precursor bodies (NPBs), are compact and morphologically different from nucleoli in somatic cells. We applied a unique NPB analyzing method ?enucleolation? technique to zygotes to remove the NPBs. It has been reported that oocyte NPBs are essential for embryonic development; in their absence, the oocytes complete maturation and can be fertilized, but no nucleoli are formed in the zygotes and embryos, leading to developmental failure. However, we found that when NPBs were removed from zygotes, the zygotes developed successfully to live-born pups. These results indicated that oocyte NPBs are essential for embryonic development, but zygote NPBs are not. In addition, the enucleolated zygotes formed somatic-type nucleoli during early embryonic development, demonstrating that somatic-type nucleoli do not originate from zygote NPBs. We summarize our recent investigation on NPBs, and provide additional comments and findings. Twit Text FOAVip Nucleolus Precursor Body (NPB): A Distinct Structure in Mammalian Oocytes and Zygotes ????Nucleus http://www.kidney.de/pget.php?&tw=1&pmid=25495074 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25495074 #FOAvip English Wikipedia <ref>{{Cite pmid|25495074}}</ref> Nucleolus Precursor Body (NPB): A Distinct Structure in Mammalian Oocytes and Zygotes #MMPMID25495074 Kyogoku H; Kitajima TS; Miyano T Nucleus 2014[]; 5 (6): 493-8 PMID25495074show ga Nucleoli in mammalian oocytes and zygotes, sometimes referred to as nucleolus precursor bodies (NPBs), are compact and morphologically different from nucleoli in somatic cells. We applied a unique NPB analyzing method ?enucleolation? technique to zygotes to remove the NPBs. It has been reported that oocyte NPBs are essential for embryonic development; in their absence, the oocytes complete maturation and can be fertilized, but no nucleoli are formed in the zygotes and embryos, leading to developmental failure. However, we found that when NPBs were removed from zygotes, the zygotes developed successfully to live-born pups. These results indicated that oocyte NPBs are essential for embryonic development, but zygote NPBs are not. In addition, the enucleolated zygotes formed somatic-type nucleoli during early embryonic development, demonstrating that somatic-type nucleoli do not originate from zygote NPBs. We summarize our recent investigation on NPBs, and provide additional comments and findings. äNucleolus Precursor Body (NPB): A Distinct Structure in Mammalian Oocy(epmc).pdf DeepDyve Pubget Overpricing