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.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 J+Ultrason
2013 ; 13
(52
): 21-30
Nephropedia Template TP
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English Wikipedia
Ultrasound and echocardiographic findings obtained in the second and third
trimesters of gestation in fetuses with normal karyotype and increased nuchal
translucency
#MMPMID26673632
Moczulska H
; Janiak K
; S?odki M
; Respondek-Liberska M
J Ultrason
2013[Mar]; 13
(52
): 21-30
PMID26673632
show ga
INTRODUCTION: Numerous papers have proven that an increased nuchal translucency
is connected with a raised risk of chromosomal aberrations, but few analyses are
related to the further state of fetuses with a normal karyotype. THE AIM OF THE
STUDY: The aim of the study was to estimate the risk of cardiac defects and other
developmental disorders in fetuses with increased nuchal translucency and normal
findings of a standard cytogenetic examination. METHODS: The authors carried out
a retrospective analysis of 5183 examinations of 3376 patients who reported to
the Department of Diagnosis and Prophylaxis of Congenital Malformations in the
Polish Mother's Memorial Hospital in ?ód? in the period from January 2008 to
March 2011 for prenatal ultrasound and echocardiographic examinations. The
authors analyzed the results of the examinations performed in the second and
third trimesters of gestation in fetuses with an increased nuchal translucency of
?3 mm in the first trimester and with a normal karyotype. RESULTS: Fifty-seven
patients (1.7% of the examined group) fulfilled the criteria necessary to be
included in the study. In 31 pregnant women (54%) structural defects or anomalies
of the fetus were found. Cardiac anomalies were detected in 17 fetuses (29.8%).
The authors detected various types of cardiac defects such as tetralogy of
Fallot, ventricular septal defect, atrioventricular septal defect, transposition
of the great arteries and hypoplastic left heart syndrome. CONCLUSIONS: In more
than half of the fetuses with an increased nuchal translucency (NT ? 3 mm) and a
normal karyotype, developmental defects of various organs appeared in the further
course of pregnancy: mainly heart defects that were either isolated, or
accompanied other anomalies.