Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=26539086
&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests
in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215
Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\26539086
.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 Front+Syst+Neurosci
2015 ; 9
(ä): 142
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Neural plasticity in hypocretin neurons: the basis of hypocretinergic regulation
of physiological and behavioral functions in animals
#MMPMID26539086
Gao XB
; Hermes G
Front Syst Neurosci
2015[]; 9
(ä): 142
PMID26539086
show ga
The neuronal system that resides in the perifornical and lateral hypothalamus
(Pf/LH) and synthesizes the neuropeptide hypocretin/orexin participates in
critical brain functions across species from fish to human. The hypocretin system
regulates neural activity responsible for daily functions (such as sleep/wake
homeostasis, energy balance, appetite, etc.) and long-term behavioral changes
(such as reward seeking and addiction, stress response, etc.) in animals. The
most recent evidence suggests that the hypocretin system undergoes substantial
plastic changes in response to both daily fluctuations (such as food intake and
sleep-wake regulation) and long-term changes (such as cocaine seeking) in
neuronal activity in the brain. The understanding of these changes in the
hypocretin system is essential in addressing the role of the hypocretin system in
normal physiological functions and pathological conditions in animals and humans.
In this review, the evidence demonstrating that neural plasticity occurs in
hypocretin-containing neurons in the Pf/LH will be presented and possible
physiological, behavioral, and mental health implications of these findings will
be discussed.