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2014 ; 271
(2
): 452-60
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MR imaging of the prostate and adjacent anatomic structures before, during, and
after ejaculation: qualitative and quantitative evaluation
#MMPMID24495265
Medved M
; Sammet S
; Yousuf A
; Oto A
Radiology
2014[May]; 271
(2
): 452-60
PMID24495265
show ga
PURPOSE: To determine the possibility of obtaining high-quality magnetic
resonance (MR) images before, during, and immediately after ejaculation and
detecting measurable changes in quantitative MR imaging parameters after
ejaculation. MATERIALS AND METHODS: In this prospective, institutional review
board-approved, HIPAA-compliant study, eight young healthy volunteers (median
age, 22.5 years), after providing informed consent, underwent MR imaging while
masturbating to the point of ejaculation. A 1.5-T MR imaging unit was used, with
an eight-channel surface coil and a dynamic single-shot fast spin-echo sequence.
In addition, a quantitative MR imaging protocol that allowed calculation of T1,
T2, and apparent diffusion coefficient (ADC) values was applied before and after
ejaculation. Volumes of the prostate and seminal vesicles (SV) were calculated by
using whole-volume segmentation on T2-weighted images, both before and after
ejaculation. Pre- and postejaculation changes in quantitative MR parameters and
measured volumes were evaluated by using the Wilcoxon signed rank test with
Bonferroni adjustment. RESULTS: There was no significant change in prostate
volumes on pre- and postejaculation images, while the SV contracted by 41% on
average (median, 44.5%; P = .004). No changes before and after ejaculation were
observed in T1 values or in T2 and ADC values in the central gland, while T2 and
ADC values were significantly reduced in the peripheral zone by 12% and 14%,
respectively (median, 13% and 14.5%, respectively; P = .004). CONCLUSION:
Successful dynamic MR imaging of ejaculation events and the ability to visualize
internal sphincter closure, passage of ejaculate, and significant changes in SV
volumes were demonstrated. Significant changes in peripheral zone T2 and ADC
values were observed.