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2015 ; 56
(10
): 695-702
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Comparison of computed tomography findings between renal oncocytomas and
chromophobe renal cell carcinomas
#MMPMID26495070
Choi JH
; Kim JW
; Lee JY
; Han WK
; Rha KH
; Choi YD
; Hong SJ
; Yoon YE
Korean J Urol
2015[Oct]; 56
(10
): 695-702
PMID26495070
show ga
PURPOSE: To investigate and distinguish the computed tomography (CT)
characteristics of chromophobe renal cell carcinoma (chRCC) and renal oncocytoma.
MATERIALS AND METHODS: Fifty-one patients with renal oncocytoma and 120 patients
with chRCC, diagnosed by surgery between November 2005 and June 2015, were
studied retrospectively. Two observers, who were urologists and unaware of the
pathological results, reviewed the preoperative CT images. The tumors were
evaluated for size, laterality, tumor type (ball or bean pattern), central
stellate scar, segmental enhancement inversion, and angular interface pattern and
tumor complexity. To accurately analyze the mass-enhancing pattern of renal mass,
we measured Hounsfield units (HUs) in each phase and analyzed the mean, maximum,
and minimum HU values and standard deviations. RESULTS: There were 51 renal
oncocytomas and 120 chRCCs in the study cohort. No differences in clinical and
demographic characteristics were observed between the two groups. A central
stellate scar and segmental enhancement inversion were more likely in
oncocytomas. However, there were no differences in ball-/bean-type
categorization, enhancement pattern, and the shape of the interface between the
groups. Higher HU values tended to be present in the corticomedullary and
nephrogenic phases in oncocytomas than in chRCC. Receiver-operating
characteristic curve analysis showed that the presence of a central stellate scar
and higher mean HU values in the nephrogenic phase were highly predictive of
renal oncocytoma (area under the curve=0.817, p<0.001). CONCLUSIONS: The
appearance of a central stellate scar and higher mean HU values in the
nephrogenic phase could be useful to distinguish renal oncocytomas from chRCCs.