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10.2147/NDT.S88569 http://scihub22266oqcxt.onion/10.2147/NDT.S88569 C4610773!4610773 !26508862     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=26508862 &cmd=llinks): Failed to open stream: HTTP request failed! 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Off-label use of transmucosal ketamine as a rapid-acting antidepressant: a retrospective chart review |pdf=|usr=}}{{26508862 }} gab.com Text Off-label use of transmucosal ketamine as a rapid-acting antidepressant: a retrospective chart review JO: Neuropsychiatr Dis Treat http://www.kidney.de/pget.php?&tw=1&pmid=26508862 #FOAvip OBJECTIVE: This study evaluated the effectiveness and safety of subanesthetic doses of ketamine using an off-label, transmucosal administration route in patients with treatment-resistant depression. METHODS: A retrospective chart review was conducted to identify patients who met the inclusion criteria for treatment-resistant major depressive disorder. Seventeen such patients who received subanesthetic doses of ketamine were included. Patient demographics, efficacy (drug refill, clinician notes), side effects, and concurrent medications were assessed. RESULTS: Benefit from low-dose transmucosal ketamine was noted in 76% of subjects (average age 48 years, 88% female), with a dose duration lasting 7-14 days. No notable side effects were noted. The most common classes of concurrent medications to which ketamine was added were serotonin-norepinephrine reuptake inhibitors (59%), stimulants (47%), folate replacement (47%), and benzodiazepines (47%). CONCLUSION: Our results provide preliminary evidence of the effectiveness and safety of low-dose transmucosal ketamine in treatment-resistant patients. A controlled, prospective pilot study is warranted to validate these findings. Twit Text FOAVip Off-label use of transmucosal ketamine as a rapid-acting antidepressant: a retrospective chart review ????Neuropsychiatr Dis Treat http://www.kidney.de/pget.php?&tw=1&pmid=26508862 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26508862 #FOAvip English Wikipedia <ref>{{Cite pmid|26508862 }}</ref> Off-label use of transmucosal ketamine as a rapid-acting antidepressant: a retrospective chart review #MMPMID26508862 Nguyen L ; Marshalek PJ ; Weaver CB ; Cramer KJ ; Pollard SE ; Matsumoto RR Neuropsychiatr Dis Treat 2015[]; 11 (ä): 2667-73 PMID26508862 show ga OBJECTIVE: This study evaluated the effectiveness and safety of subanesthetic doses of ketamine using an off-label, transmucosal administration route in patients with treatment-resistant depression. METHODS: A retrospective chart review was conducted to identify patients who met the inclusion criteria for treatment-resistant major depressive disorder. Seventeen such patients who received subanesthetic doses of ketamine were included. Patient demographics, efficacy (drug refill, clinician notes), side effects, and concurrent medications were assessed. RESULTS: Benefit from low-dose transmucosal ketamine was noted in 76% of subjects (average age 48 years, 88% female), with a dose duration lasting 7-14 days. No notable side effects were noted. The most common classes of concurrent medications to which ketamine was added were serotonin-norepinephrine reuptake inhibitors (59%), stimulants (47%), folate replacement (47%), and benzodiazepines (47%). CONCLUSION: Our results provide preliminary evidence of the effectiveness and safety of low-dose transmucosal ketamine in treatment-resistant patients. A controlled, prospective pilot study is warranted to validate these findings. äOff-label use of transmucosal ketamine as a rapid-acting antidepressan(epmc).pdf DeepDyve Pubget Overpricing