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2015 ; 2015
(ä): 545674
Nephropedia Template TP
gab.com Text
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English Wikipedia
Assessment of Hair Aluminum, Lead, and Mercury in a Sample of Autistic Egyptian
Children: Environmental Risk Factors of Heavy Metals in Autism
#MMPMID26508811
Mohamed Fel B
; Zaky EA
; El-Sayed AB
; Elhossieny RM
; Zahra SS
; Salah Eldin W
; Youssef WY
; Khaled RA
; Youssef AM
Behav Neurol
2015[]; 2015
(ä): 545674
PMID26508811
show ga
BACKGROUND AND AIMS: The etiological factors involved in the etiology of autism
remain elusive and controversial, but both genetic and environmental factors have
been implicated. The aim of this study was to assess the levels and possible
environmental risk factors and sources of exposure to mercury, lead, and aluminum
in children with autism spectrum disorder (ASD) as compared to their matched
controls. METHODS: One hundred ASD children were studied in comparison to 100
controls. All participants were subjected to clinical evaluation and measurement
of mercury, lead, and aluminum through hair analysis which reflects past
exposure. RESULTS: The mean Levels of mercury, lead, and aluminum in hair of the
autistic patients were significantly higher than controls. Mercury, lead, and
aluminum levels were positively correlated with maternal fish consumptions,
living nearby gasoline stations, and the usage of aluminum pans, respectively.
CONCLUSION: Levels of mercury, lead, and aluminum in the hair of autistic
children are higher than controls. Environmental exposure to these toxic heavy
metals, at key times in development, may play a causal role in autism.