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10.1111/cei.12679

http://scihub22266oqcxt.onion/10.1111/cei.12679
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C4608508!4608508!26153037
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suck abstract from ncbi


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pmid26153037      Clin+Exp+Immunol 2015 ; 182 (2): 184-94
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  • Expression of CD11c and EMR2 on neutrophils: potential diagnostic biomarkers for sepsis and systemic inflammation #MMPMID26153037
  • Lewis SM; Treacher DF; Edgeworth J; Mahalingam G; Brown CS; Mare TA; Stacey M; Beale R; Brown K
  • Clin Exp Immunol 2015[Nov]; 182 (2): 184-94 PMID26153037show ga
  • There is a need for cellular biomarkers to differentiate patients with sepsis from those with the non-infectious systemic inflammatory response syndrome (SIRS). In this double-blind study we determined whether the expression of known (CD11a/b/c, CD62L) and putative adhesion molecules [CD64, CD97 and epidermal growth factor (EGF)-like molecule containing mucin-like hormone receptor (EMR2)] on blood neutrophils could serve as useful biomarkers of infection and of non-infectious SIRS in critically ill patients. We studied 103 patients with SIRS, 83 of whom had sepsis, and 50 healthy normal subjects, using flow cytometry to characterize neutrophils phenotypically in whole blood samples. Patients with SIRS had an increased prevalence of neutrophils expressing CD11c, CD64 and EMR2 in comparison with healthy subjects (P?
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