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10.1007/978-1-60327-325-1_14 http://scihub22266oqcxt.onion/10.1007/978-1-60327-325-1_14 C4607074!4607074!20552433     free     free     free Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Methods+Mol+Biol 2010 ; 652 (ä): 247-61 Nephropedia Template TP {{tp|p=20552433|t=2010. Visualization of Retinoid Storage and Trafficking by Two-Photon Microscopy |pdf=|usr=}}{{20552433}} gab.com Text Visualization of Retinoid Storage and Trafficking by Two-Photon Microscopy JO: Methods Mol Biol http://www.kidney.de/pget.php?&tw=1&pmid=20552433 #FOAvip Vertebrate vision is maintained by the retinoid (visual) cycle, a complex enzymatic pathway that operates in the retina to regenerate the visual chromophore, 11-cis-retinal, a prosthetic group of rhodopsin that undergoes activation by light. Many different mutations in genes encoding retinoid cycle proteins can cause a variety of human blinding diseases. Two-photon microscopy is an evolving, non-invasive, and repetitive imaging technology that can be used to monitor biomolecules within the vertebrate retina at a subcellular resolution. This method has the great advantage of portraying endogenous retinoid fluorophores in their native state without the need for artificial staining. Such real-time retinal imaging permits rapid evaluation not only of various stages of retinal disease in live animal models of human retinopathies but also of the outcome from intended pharmacological therapies. Two-photon microscopy offers substantial potential for early detection of age- and disease-related changes in the eye, long before clinical or pathological manifestations become apparent. Twit Text FOAVip Visualization of Retinoid Storage and Trafficking by Two-Photon Microscopy ????Methods Mol Biol http://www.kidney.de/pget.php?&tw=1&pmid=20552433 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=20552433 #FOAvip English Wikipedia <ref>{{Cite pmid|20552433}}</ref> Visualization of Retinoid Storage and Trafficking by Two-Photon Microscopy #MMPMID20552433 Imanishi Y; Palczewski K Methods Mol Biol 2010[]; 652 (ä): 247-61 PMID20552433show ga Vertebrate vision is maintained by the retinoid (visual) cycle, a complex enzymatic pathway that operates in the retina to regenerate the visual chromophore, 11-cis-retinal, a prosthetic group of rhodopsin that undergoes activation by light. Many different mutations in genes encoding retinoid cycle proteins can cause a variety of human blinding diseases. Two-photon microscopy is an evolving, non-invasive, and repetitive imaging technology that can be used to monitor biomolecules within the vertebrate retina at a subcellular resolution. This method has the great advantage of portraying endogenous retinoid fluorophores in their native state without the need for artificial staining. Such real-time retinal imaging permits rapid evaluation not only of various stages of retinal disease in live animal models of human retinopathies but also of the outcome from intended pharmacological therapies. Two-photon microscopy offers substantial potential for early detection of age- and disease-related changes in the eye, long before clinical or pathological manifestations become apparent. äVisualization of Retinoid Storage and Trafficking by Two-Photon Micros(epmc).pdf DeepDyve Pubget Overpricing