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10.1038/srep15015 http://scihub22266oqcxt.onion/10.1038/srep15015 C4606562!4606562!26468932     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Sci+Rep 2015 ; 5 (ä): ä Nephropedia Template TP {{tp|p=26468932|t=2015. Different Brain Regions are Infected with Fungi in Alzheimer?s Disease |pdf=|usr=}}{{26468932}} gab.com Text Different Brain Regions are Infected with Fungi in Alzheimer s Disease JO: Sci Rep http://www.kidney.de/pget.php?&tw=1&pmid=26468932 #FOAvip The possibility that Alzheimer?s disease (AD) has a microbial aetiology has been proposed by several researchers. Here, we provide evidence that tissue from the central nervous system (CNS) of AD patients contain fungal cells and hyphae. Fungal material can be detected both intra- and extracellularly using specific antibodies against several fungi. Different brain regions including external frontal cortex, cerebellar hemisphere, entorhinal cortex/hippocampus and choroid plexus contain fungal material, which is absent in brain tissue from control individuals. Analysis of brain sections from ten additional AD patients reveals that all are infected with fungi. Fungal infection is also observed in blood vessels, which may explain the vascular pathology frequently detected in AD patients. Sequencing of fungal DNA extracted from frozen CNS samples identifies several fungal species. Collectively, our findings provide compelling evidence for the existence of fungal infection in the CNS from AD patients, but not in control individuals. Twit Text FOAVip Different Brain Regions are Infected with Fungi in Alzheimer s Disease ????Sci Rep http://www.kidney.de/pget.php?&tw=1&pmid=26468932 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26468932 #FOAvip English Wikipedia <ref>{{Cite pmid|26468932}}</ref> Different Brain Regions are Infected with Fungi in Alzheimer?s Disease #MMPMID26468932 Pisa D; Alonso R; Rábano A; Rodal I; Carrasco L Sci Rep 2015[]; 5 (ä): ä PMID26468932show ga The possibility that Alzheimer?s disease (AD) has a microbial aetiology has been proposed by several researchers. Here, we provide evidence that tissue from the central nervous system (CNS) of AD patients contain fungal cells and hyphae. Fungal material can be detected both intra- and extracellularly using specific antibodies against several fungi. Different brain regions including external frontal cortex, cerebellar hemisphere, entorhinal cortex/hippocampus and choroid plexus contain fungal material, which is absent in brain tissue from control individuals. Analysis of brain sections from ten additional AD patients reveals that all are infected with fungi. Fungal infection is also observed in blood vessels, which may explain the vascular pathology frequently detected in AD patients. Sequencing of fungal DNA extracted from frozen CNS samples identifies several fungal species. Collectively, our findings provide compelling evidence for the existence of fungal infection in the CNS from AD patients, but not in control individuals. äDifferent Brain Regions are Infected with Fungi in Alzheimer?s Disease(epmc).pdf DeepDyve Pubget Overpricing