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10.7860/JCDR/2015/14962.6456 http://scihub22266oqcxt.onion/10.7860/JCDR/2015/14962.6456 C4606264!4606264!26500935     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Clin+Diagn+Res 2015 ; 9 (9): OC13-6 Nephropedia Template TP {{tp|p=26500935|t=2015. Anti-perinuclear Factor as Diagnostic Marker in Rheumatoid Arthritis |pdf=|usr=}}{{26500935}} gab.com Text Anti-perinuclear Factor as Diagnostic Marker in Rheumatoid Arthritis JO: J Clin Diagn Res http://www.kidney.de/pget.php?&tw=1&pmid=26500935 #FOAvip Introduction: Rheumatoid Arthritis (RA) is a systemic autoimmune disease. It is associated with several auto antibodies which can serve as diagnostic and prognostic markers. Aim: In this study, Anti perinuclear Factor (APF) was evaluated as a biomarker in comparison with Rheumatoid Factor (RF) in Rheumatoid Arthritis. Materials and Methods: Fifty two sera of patients with RA (mean age 48±15.8), 23 sera of Patient control group (mean age 32.5 ± 16.9) and 30 sera of Healthy control group (mean age 32.1± 16.9) were analysed. The method is based on the binding of APF to perinuclear keratohyalin granules of buccal mucosal cell and its detection using a fluorescently labeled anti human total antiserum. Results:: APF were found in 71.2 %(37/52) of patients with RA. The sensitivity and specificity for APF from 1/5 serum dilution was 71.2% and 94.3% respectively. RF test had higher sensitivity (88.5%) compare to the APF test (71.2%), but its specificity was (86.8%) less than APF (94.3%).There was no significant relationship between the onset of APF and severity of disease but there was significant relationship between the APF titer and severity of disease (p<0.05). Conclusion: It is concluded that APF test is a valuable serological tool for the diagnosis of the disease and a useful serological marker to differentiate from the other inflammatory rheumatoid diseases. Twit Text FOAVip Anti-perinuclear Factor as Diagnostic Marker in Rheumatoid Arthritis ????J Clin Diagn Res http://www.kidney.de/pget.php?&tw=1&pmid=26500935 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26500935 #FOAvip English Wikipedia <ref>{{Cite pmid|26500935}}</ref> Anti-perinuclear Factor as Diagnostic Marker in Rheumatoid Arthritis #MMPMID26500935 Abedian Z; Sagafi M; Kenari SA; Abedian F J Clin Diagn Res 2015[Sep]; 9 (9): OC13-6 PMID26500935show ga Introduction: Rheumatoid Arthritis (RA) is a systemic autoimmune disease. It is associated with several auto antibodies which can serve as diagnostic and prognostic markers. Aim: In this study, Anti perinuclear Factor (APF) was evaluated as a biomarker in comparison with Rheumatoid Factor (RF) in Rheumatoid Arthritis. Materials and Methods: Fifty two sera of patients with RA (mean age 48±15.8), 23 sera of Patient control group (mean age 32.5 ± 16.9) and 30 sera of Healthy control group (mean age 32.1± 16.9) were analysed. The method is based on the binding of APF to perinuclear keratohyalin granules of buccal mucosal cell and its detection using a fluorescently labeled anti human total antiserum. Results:: APF were found in 71.2 %(37/52) of patients with RA. The sensitivity and specificity for APF from 1/5 serum dilution was 71.2% and 94.3% respectively. RF test had higher sensitivity (88.5%) compare to the APF test (71.2%), but its specificity was (86.8%) less than APF (94.3%).There was no significant relationship between the onset of APF and severity of disease but there was significant relationship between the APF titer and severity of disease (p<0.05). Conclusion: It is concluded that APF test is a valuable serological tool for the diagnosis of the disease and a useful serological marker to differentiate from the other inflammatory rheumatoid diseases. äAnti-perinuclear Factor as Diagnostic Marker in Rheumatoid Arthritis (epmc).pdf DeepDyve Pubget Overpricing