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10.3233/ACP-140087 http://scihub22266oqcxt.onion/10.3233/ACP-140087 C4605481!4605481!24503545     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Anal+Cell+Pathol+(Amst) 2013 ; 36 (5-6): 133-47 Nephropedia Template TP {{tp|p=24503545|t=2013. Expression of WW Domain-Containing Oxidoreductase WOX1 in Human Nervous System Tumors |pdf=|usr=}}{{24503545}} gab.com Text Expression of WW Domain-Containing Oxidoreductase WOX1 in Human Nervous System Tumors JO: Anal Cell Pathol (Amst) http://www.kidney.de/pget.php?&tw=1&pmid=24503545 #FOAvip Background and ObjectiveS: We aimed to evaluate the expression levels of the tumor suppressor WOX1 in nervous system tumors and its co-expression with p53 and neurofibromatosis type 2/merlin (NF2) tumor suppressor gene products.Methods: Immunohistochemistry, western blotting and in situ hybridization were used for WOX1 protein and WWOX mRNA expression. Immunofluorescence and electron microscopical immunohistochemistry were performed for colocalization of gene products.Results: WOX1 expression is low in normal cortical neurons, mainly on the axon fibers, whereas there is moderate to high immunoreactivity in the cytosol and nuclei of certain tumor cells. In the microcystic (WHO grade I) and malignant (WHO grade III) meningiomas, WOX1 expression is intense, but various in transitional (WHO grade I) and atypical (WHO grade II) subtypes. WOX1 levels are moderate to high in the menigiotheliomatous area, but relatively low in the fibroblastic area. WOX1 and NF2/merlin, but not p53, colocalized in certain tumor cells, primarily at the borders of nuclei. Schwannoma and astrocytoma specimens stained moderately to strongly positive for the WOX1 protein. Interestingly, the expression of WOX1, NF2/merlin and mutant p53 is intense in high grade glioblastoma, but WOX1 expression is low in metastatic carcinoma or adenocarcinoma.Conclusions: The expression of WOX1 on different types of nervous system tumors, including primary and metastatic tumors, is differential. Twit Text FOAVip Expression of WW Domain-Containing Oxidoreductase WOX1 in Human Nervous System Tumors ????Anal Cell Pathol (Amst) http://www.kidney.de/pget.php?&tw=1&pmid=24503545 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=24503545 #FOAvip English Wikipedia <ref>{{Cite pmid|24503545}}</ref> Expression of WW Domain-Containing Oxidoreductase WOX1 in Human Nervous System Tumors #MMPMID24503545 Chiang MF; Chen ST; Lo CP; Sze CI; Chang NS; Chen YJ Anal Cell Pathol (Amst) 2013[]; 36 (5-6): 133-47 PMID24503545show ga Background and ObjectiveS: We aimed to evaluate the expression levels of the tumor suppressor WOX1 in nervous system tumors and its co-expression with p53 and neurofibromatosis type 2/merlin (NF2) tumor suppressor gene products.Methods: Immunohistochemistry, western blotting and in situ hybridization were used for WOX1 protein and WWOX mRNA expression. Immunofluorescence and electron microscopical immunohistochemistry were performed for colocalization of gene products.Results: WOX1 expression is low in normal cortical neurons, mainly on the axon fibers, whereas there is moderate to high immunoreactivity in the cytosol and nuclei of certain tumor cells. In the microcystic (WHO grade I) and malignant (WHO grade III) meningiomas, WOX1 expression is intense, but various in transitional (WHO grade I) and atypical (WHO grade II) subtypes. WOX1 levels are moderate to high in the menigiotheliomatous area, but relatively low in the fibroblastic area. WOX1 and NF2/merlin, but not p53, colocalized in certain tumor cells, primarily at the borders of nuclei. Schwannoma and astrocytoma specimens stained moderately to strongly positive for the WOX1 protein. Interestingly, the expression of WOX1, NF2/merlin and mutant p53 is intense in high grade glioblastoma, but WOX1 expression is low in metastatic carcinoma or adenocarcinoma.Conclusions: The expression of WOX1 on different types of nervous system tumors, including primary and metastatic tumors, is differential. äExpression of WW Domain-Containing Oxidoreductase WOX1 in Human Nervou(epmc).pdf DeepDyve Pubget Overpricing