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10.1186/s12879-015-1144-0 http://scihub22266oqcxt.onion/10.1186/s12879-015-1144-0 C4604726!4604726 !26463900     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=26463900 &cmd=llinks): Failed to open stream: HTTP request failed! 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Necrotizing fasciitis in patients with diabetes mellitus: clinical characteristics and risk factors for mortality |pdf=|usr=}}{{26463900 }} gab.com Text Necrotizing fasciitis in patients with diabetes mellitus: clinical characteristics and risk factors for mortality JO: BMC Infect Dis http://www.kidney.de/pget.php?&tw=1&pmid=26463900 #FOAvip BACKGROUND: Necrotizing fasciitis (NF) is a rapidly progressive and life-threatening infection. This study aimed to investigate the clinical characteristics and mortality- associated factors in diabetic patients. METHODS: Detailed clinical information of 165 NF cases was retrospectively collected and analyzed in National Taiwan University Hospital between January 1997 and February 2013. We documented and compared the clinical features according to the presence of underlying diabetes mellitus, and we identified risk factors associated with mortality. RESULTS: There were 84 patients (51 %) with diabetes. The overall case fatality rate was 29.7 %, and we found no significant difference between the patients with or without diabetes. Compared with the nondiabetic patients, diabetic patients were older and exhibited higher serum levels of glucose and potassium on admission. Polymicrobial infection and monomicrobial NF caused by Klebsiella pneumoniae were also more frequently associated with diabetic patients. Moreover, diabetic NF patients exhibit a significantly higher chance of limb loss during hospitalization. In the combined diabetic and nondiabetic cohort, a high serum level of potassium (odds ratio, 2.2; 95 % confidence interval, 1.2 to 4.02; P?=?0.011) on admission was independently associated with mortality, whereas positive blood culture on admission was associated with mortality in the diabetic cohort (odds ratio, 7.36; 95 % confidence interval, 1.66 to 32.54; P?=?0.009). CONCLUSIONS: Diabetic patients are more susceptible to NF caused by polymicrobial infection or K. pneumoniae, and they are more likely to receive limb amputation for infection control. Bacteraemia on admission is a significant risk factor for mortality in diabetic NF patients. Twit Text FOAVip Necrotizing fasciitis in patients with diabetes mellitus: clinical characteristics and risk factors for mortality ????BMC Infect Dis http://www.kidney.de/pget.php?&tw=1&pmid=26463900 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26463900 #FOAvip English Wikipedia <ref>{{Cite pmid|26463900 }}</ref> Necrotizing fasciitis in patients with diabetes mellitus: clinical characteristics and risk factors for mortality #MMPMID26463900 Cheng NC ; Tai HC ; Chang SC ; Chang CH ; Lai HS BMC Infect Dis 2015[Oct]; 15 (ä): 417 PMID26463900 show ga BACKGROUND: Necrotizing fasciitis (NF) is a rapidly progressive and life-threatening infection. This study aimed to investigate the clinical characteristics and mortality- associated factors in diabetic patients. METHODS: Detailed clinical information of 165 NF cases was retrospectively collected and analyzed in National Taiwan University Hospital between January 1997 and February 2013. We documented and compared the clinical features according to the presence of underlying diabetes mellitus, and we identified risk factors associated with mortality. RESULTS: There were 84 patients (51 %) with diabetes. The overall case fatality rate was 29.7 %, and we found no significant difference between the patients with or without diabetes. Compared with the nondiabetic patients, diabetic patients were older and exhibited higher serum levels of glucose and potassium on admission. Polymicrobial infection and monomicrobial NF caused by Klebsiella pneumoniae were also more frequently associated with diabetic patients. Moreover, diabetic NF patients exhibit a significantly higher chance of limb loss during hospitalization. In the combined diabetic and nondiabetic cohort, a high serum level of potassium (odds ratio, 2.2; 95 % confidence interval, 1.2 to 4.02; P?=?0.011) on admission was independently associated with mortality, whereas positive blood culture on admission was associated with mortality in the diabetic cohort (odds ratio, 7.36; 95 % confidence interval, 1.66 to 32.54; P?=?0.009). CONCLUSIONS: Diabetic patients are more susceptible to NF caused by polymicrobial infection or K. pneumoniae, and they are more likely to receive limb amputation for infection control. Bacteraemia on admission is a significant risk factor for mortality in diabetic NF patients. |Adult [MESH] |Aged [MESH] |Amputation, Surgical [MESH] |Bacteremia/complications/mortality [MESH] |Comorbidity [MESH] |Diabetes Complications/etiology/*mortality/surgery [MESH] |Diabetes Mellitus/mortality [MESH] |Fasciitis, Necrotizing/etiology/*mortality/therapy [MESH] |Female [MESH] |Hospitals, University/statistics & numerical data [MESH] |Humans [MESH] |Klebsiella Infections/etiology/mortality [MESH] |Klebsiella pneumoniae/pathogenicity [MESH] |Male [MESH] |Middle Aged [MESH] |Odds Ratio [MESH] |Potassium/blood [MESH] |Retrospective Studies [MESH] |Risk Factors [MESH]Necrotizing fasciitis in patients with diabetes mellitus: clinical c(epmc).pdf DeepDyve Pubget Overpricing