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2015 ; 15
(ä): 85
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Classification and prevalence of spin in abstracts of non-randomized studies
evaluating an intervention
#MMPMID26462565
Lazarus C
; Haneef R
; Ravaud P
; Boutron I
BMC Med Res Methodol
2015[Oct]; 15
(ä): 85
PMID26462565
show ga
BACKGROUND: Spin represents specific reporting strategies, either intentional or
unintentional, to convince the reader that the beneficial effect of the
experimental intervention in terms of efficacy and safety is greater than that
shown by the results. The objectives of this study were to 1) develop a
classification of spin specific to non-randomized studies assessing an
intervention and 2) estimate the prevalence of spin in abstracts of reports of
such studies. METHODS: In a first step, we developed a specific classification of
spin for non-randomized studies by a literature review and pilot study. In a
second step, 2 researchers trained in the field of methodology evaluated the
prevalence of spin in the abstract of all non-randomized studies assessing an
intervention published in the BioMed Central Medical Series journals between
January 1, 2011 and December 31, 2013. All disagreements were resolved by
consensus. We also determined whether the level of spin in abstract conclusions
was high (spin reported without uncertainty or recommendations for further
trials), moderate (spin reported with some uncertainty or recommendations for
further trials) or low (spin reported with uncertainty and recommendations for
further trials). RESULTS: Among the 128 assessed articles assessed, 107 (84%) had
at least one example of spin in their abstract. The most prevalent strategy of
spin was the use of causal language, identified in 68 (53%) abstracts. Other
frequent strategies were linguistic spin, inadequate implications for clinical
practice, and lack of focus on harm, identified in 33 (26%), 25 (20%), and 34
(27%) abstracts respectively. Abstract conclusions of 61 (48%) articles featured
a high level of spin. CONCLUSION: Abstract of reports of non-randomized studies
assessing an intervention frequently includes spin. Efforts to reduce the
prevalence of spin in abstract for such studies are needed.