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Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Arch+Neurosci 2015 ; 2 (4): ä Nephropedia Template TP
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Cervical Artery Dissection: A Review of the Epidemiology, Pathophysiology, Treatment, and Outcome #MMPMID26478890
Blum CA; Yaghi S
Arch Neurosci 2015[Oct]; 2 (4): ä PMID26478890show ga
Context: Cervical artery dissection (CAD) is a common cause of stroke in young adults. There is controversy over whether anticoagulation is superior to antiplatelet therapy in preventing stroke in patients with CAD, although meta-analyses to date have not shown any difference between the two treatments. Evidence acquisition: We performed a PubMed search using each of the keywords: ?Cervical artery dissection?, ?Dissection?, ?Carotid dissection?, and ?Vertebral dissection? between January 1st, 1990 and July 1st 2015. We identified evidence-based peer-reviewed articles, including randomized trials, case series and reports, and retrospective reviews that encompass the epidemiology, clinical manifestations, pathophysiology, treatment, and outcome of cervical artery dissection. Results: This paper highlights the mechanisms of cervical artery dissection and stroke in patients with dissection as well as the natural history and treatment. Conclusion: Given the relatively rare incidence of this disease, multicenter studies with collaborative effort among stroke centers worldwide should be considered to enroll patients with cervical artery dissection in a randomized trial comparing the two treatments.