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10.1016/j.jss.2015.04.046 http://scihub22266oqcxt.onion/10.1016/j.jss.2015.04.046 C4604005!4604005!25982045     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Surg+Res 2015 ; 199 (1): 115-20 Nephropedia Template TP {{tp|p=25982045|t=2015. KDIGO guidelines and parathyroidectomy for renal hyperparathyroidism |pdf=|usr=}}{{25982045}} gab.com Text KDIGO guidelines and parathyroidectomy for renal hyperparathyroidism JO: J Surg Res http://www.kidney.de/pget.php?&tw=1&pmid=25982045 #FOAvip Introduction: Patients with end stage renal disease(ESRD) develop hypocalcemia, resulting in secondary hyperparathyroidism(SHPT). No clear criterions exist to aid in surgical decision making for SHPT. The 2009 Kidney Disease: Improving Global Outcomes(KDIGO) guidelines provide target ranges for serum calcium, phosphate and parathyroid hormone(PTH) levels in patients with ESRD. Parathyroidectomy can help achieve these targets. The study purpose is to examine how parathyroidectomy for SHPT impacts KDIGO targets during immediate and long-term follow-up, and to evaluate KDIGO categorization with receipt of additional surgical intervention. Methods: A retrospective review of a prospective parathyroidectomy database was performed. Included patients had SHPT, were on dialysis and underwent parathyroidectomy. Calcium, phosphate and PTH values were classified as below, within, or above KDIGO targets. Results: Between 2000 and 2013, 36 patients with SHPT met criteria. Subtotal parathyroidectomy was performed in 89%, total parathyroidectomy in 11%. Follow-up time was 54±7 months. 8 patients(22%) required additional surgery. 28 patients(76%) were alive at last follow-up. At last follow up, patients had phosphate(46%), and PTH(17%) above KDIGO ranges.Factors associated with re-operation were assessed. Patient PTH within or above target immediately post-operative had a higher rate of reoperation(p<0.01). At last follow-up, higher phosphate(p=0.054) and PTH(p<0.001) were associated with higher reoperation rates, but calcium(p=0.33) was not. Conclusions: PTH and phosphate levels above KDIGO indices were associated with additional surgical intervention. Many patients had laboratory indices above range at last follow-up, suggesting more patients had persistent or recurrent disease than underwent reoperation. Patients may benefit from more aggressive medical and/or surgical management. Twit Text FOAVip KDIGO guidelines and parathyroidectomy for renal hyperparathyroidism ????J Surg Res http://www.kidney.de/pget.php?&tw=1&pmid=25982045 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25982045 #FOAvip English Wikipedia <ref>{{Cite pmid|25982045}}</ref> KDIGO guidelines and parathyroidectomy for renal hyperparathyroidism #MMPMID25982045 Oltmann SC; Madkhali TM; Sippel RS; Chen H; Schneider DF J Surg Res 2015[Nov]; 199 (1): 115-20 PMID25982045show ga Introduction: Patients with end stage renal disease(ESRD) develop hypocalcemia, resulting in secondary hyperparathyroidism(SHPT). No clear criterions exist to aid in surgical decision making for SHPT. The 2009 Kidney Disease: Improving Global Outcomes(KDIGO) guidelines provide target ranges for serum calcium, phosphate and parathyroid hormone(PTH) levels in patients with ESRD. Parathyroidectomy can help achieve these targets. The study purpose is to examine how parathyroidectomy for SHPT impacts KDIGO targets during immediate and long-term follow-up, and to evaluate KDIGO categorization with receipt of additional surgical intervention. Methods: A retrospective review of a prospective parathyroidectomy database was performed. Included patients had SHPT, were on dialysis and underwent parathyroidectomy. Calcium, phosphate and PTH values were classified as below, within, or above KDIGO targets. Results: Between 2000 and 2013, 36 patients with SHPT met criteria. Subtotal parathyroidectomy was performed in 89%, total parathyroidectomy in 11%. Follow-up time was 54±7 months. 8 patients(22%) required additional surgery. 28 patients(76%) were alive at last follow-up. At last follow up, patients had phosphate(46%), and PTH(17%) above KDIGO ranges.Factors associated with re-operation were assessed. Patient PTH within or above target immediately post-operative had a higher rate of reoperation(p<0.01). At last follow-up, higher phosphate(p=0.054) and PTH(p<0.001) were associated with higher reoperation rates, but calcium(p=0.33) was not. Conclusions: PTH and phosphate levels above KDIGO indices were associated with additional surgical intervention. Many patients had laboratory indices above range at last follow-up, suggesting more patients had persistent or recurrent disease than underwent reoperation. Patients may benefit from more aggressive medical and/or surgical management. äKDIGO guidelines and parathyroidectomy for renal hyperparathyroidism (epmc).pdf DeepDyve Pubget Overpricing