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2012 ; 12
(51
): 402-19
Nephropedia Template TP
gab.com Text
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English Wikipedia
The differentiation of the character of solid lesions in the breast in the
compression sonoelastography Part I: The diagnostic value of the ultrasound
B-mode imaging in the differentiation diagnostics of solid, focal lesions in the
breast in relation to the pathomorphological verification
#MMPMID26675530
Dobruch-Sobczak K
J Ultrason
2012[Dec]; 12
(51
): 402-19
PMID26675530
show ga
The aim of this study was to evaluate the diagnostic value of the ultrasound
B-mode imaging in the differentiation diagnostics of solid lesions in the breast
in relation to the pathomorphological verification. From January to July 2010,
375 ultrasound breast examinations were conducted. The study enrolled 80 women
aged 17-83, with 99 solid, focal lesions present in breasts, which were qualified
for pathomorphological verification on the basis of the ultrasound examination.
All patients underwent: the interview, physical examination, ultrasound
examination and sonoelastography. The ultrasound features of the lesions, their
vascularization patterns in the Doppler examination as well as the adjacent
tissues were determined. Next, the focal lesions were categorized according to
the BIRADS-US classification. The obtained results were analyzed statistically.
In the group of 80 patients, 99 focal, solid lesions in breasts were visualized,
including 39 neoplastic, malignant lesions (group I) and 60 lesions of benign
nature (group II). The malignant lesions were often characterized by: greater
size, irregular shape (34/39), prevalence of the anteroposterior dimension over
the lateral-lateral dimension (22/39), acoustic shadowing (20/39), the margins
not well-circumscribed (37/39), spiculated margins (16/39) and the presence of
calcifications (14/39). The benign lesions were much more often hyper- and
isoechogenic (14/60). In group I the lesions more often demonstrated the features
of increased vascularization (29/39) and the presence of irregularly shaped
vessels (23/29). This vascularization more often originated in the adjacent
tissues. In the surroundings of the malignant neoplastic lesions, the presence of
edema (16/39) and skin thickening (6/39) occurred more frequently and the
abnormal axillary lymph nodes were more often diagnosed. The lesions of group I
were assigned to the following BIRADS categories: BIRADS-US 4 (9 lesions) and
BIRADS-US 5 (30 lesions). In group II, there was a prevalence of BIRADS-US 3 and
4 categories (58 lesions) and 2 lesions were classified to BIRADS-US 5 category.
In the statistical analysis of the models based on BIRADS classification, it was
demonstrated that BIRADS 4 showed the highest sum of sensitivity and specificity
values of 173.6% in differentiation of the character of focal lesions in the
breast (sensitivity 76.92%, specificity 96.67%).