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10.1097/MD.0000000000001427

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suck abstract from ncbi


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pmid26313796
      Medicine+(Baltimore) 2015 ; 94 (34 ): e1427
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  • Direct Revascularization With the Angiosome Concept for Lower Limb Ischemia: A Systematic Review and Meta-Analysis #MMPMID26313796
  • Huang TY ; Huang TS ; Wang YC ; Huang PF ; Yu HC ; Yeh CH
  • Medicine (Baltimore) 2015[Aug]; 94 (34 ): e1427 PMID26313796 show ga
  • The angiosome concept provides practical information regarding the vascular anatomy of reconstructive and vascular surgery for the treatment of peripheral arterial occlusive disease and, particularly, critical lower limb ischemia.The aim of the study was to confirm the efficacy of direct revascularization with the angiosome concept (DR) for lower limb ischemia.Complementary manual searches were performed through the Pubmed, Cochrane Library, and EMBASE databases.We searched all randomized and nonrandomized studies (NRSs) comparing DR with indirect revascularization (IR) (without the angiosome concept) for lower limb ischemia. Only 9 nonrandomized controlled retrospective cohort studies were found and included. Trials published in any language were included.Primary endpoints were time to limb amputation and time to wound healing. Data extraction and trial quality assessment were performed by two authors independently. A third author was consulted for disagreements settlement and quality assurance.Five NRSs involving 779 lower limbs revealed that DR significantly improved the overall survival of limbs (hazard ratio [HR] 0.61; 95% confidence interval [CI]?=?0.46-0.80; P?
  • |Clinical Trials as Topic [MESH]
  • |Humans [MESH]
  • |Ischemia/*surgery [MESH]
  • |Lower Extremity/*blood supply [MESH]


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