Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=25546693
&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests
in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215
Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 298.79999999999995 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 298.79999999999995 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 298.79999999999995 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 298.79999999999995 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 332.4 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 332.4 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 332.4 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 332.4 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 332.4 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\25546693
.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 Medicine+(Baltimore)
2014 ; 93
(29
): e353
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Fatal necrotizing angiotropic Epstein-Barr virus-negative large B-cell lymphoma:
a case report with unusual clinicopathological features in-between lymphomatoid
granulomatosis and T-cell/histiocyte-rich large B-cell lymphoma
#MMPMID25546693
Olivieri A
; Sabattini E
; Goteri G
; Trappolini S
; Saraceni F
; Samorì A
; Gini G
; Leoni P
; Olivieri J
; Pileri SA
Medicine (Baltimore)
2014[Dec]; 93
(29
): e353
PMID25546693
show ga
In the spectrum of diffuse large B-cell lymphomas (DLBCL), both
T-cell/histiocyte-rich large B-cell lymphoma (TCHRBCL) and most lymphomatoid
granulomatosis (LG) cases are characterized by the relative rarity of the
neoplastic B-cell population, with respect to the overwhelming non-neoplastic
counterpart of T cells or histiocytes. Here we report a case of aggressive B-cell
lymphoma with unusual clinicopathological features partially overlapping these
two entities. The patient was a previously healthy 55-year-old male, presenting
with a computed tomography finding of a pelvic mass, inguinal lymphadenopathies,
and pulmonary nodules. Two excisional lymph node biopsies resulted inconclusive
for lymphoproliferative disease. Because of a colonic perforation, the patient
underwent an urgent laparotomy, which disclosed a large pelvic abscess. The
pathological examination of the surgical specimen could not discriminate between
a primary aggressive B-cell lymphoproliferative disorder and an abnormal
inflammatory hyper-reaction. The patient developed a septic state, not resolving
until death, which occurred because of an abdominal hemorrhage. A second
perimortem surgical specimen consisting of a nodal mass revealed a diagnosis of
an Epstein-Barr virus-negative high-grade large B-cell lymphoma with massive
necrosis, angiocentric pattern of growth, and prominent T-cell infiltrate. The
unique clinicopathological features did not allow to classify this tumor within
any of the recognized WHO entities, potentially representing a new
clinicopathological variant of DLBCL in-between TCHRBCL and LG.
|Fatal Outcome
[MESH]
|Histiocytes/*pathology
[MESH]
|Humans
[MESH]
|Lymphoma, B-Cell/*pathology
[MESH]
|Lymphoma, Large B-Cell, Diffuse/*pathology
[MESH]