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10.1097/MD.0000000000000885

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suck abstract from ncbi


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pmid25984681
      Medicine+(Baltimore) 2015 ; 94 (19 ): e885
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  • Early diagnosis and successful treatment of Cryptococcus albidus keratitis: a case report and literature review #MMPMID25984681
  • Huang YH ; Lin IH ; Chang TC ; Tseng SH
  • Medicine (Baltimore) 2015[May]; 94 (19 ): e885 PMID25984681 show ga
  • Cryptococcus albidus keratitis is a rare and difficult diagnosed disease. Here we report a case of C albidus keratitis early diagnosed by dot hybridization assay and successfully treated with intrastromal injection of Amphotericin B (AB).A 45-year-old man presented with left red eye for 2 days. The slit lamp examination exhibited deep corneal infiltrations. Smears and cultures were performed but revealed negative findings. Molecular detection of pathogens was performed by dot hybridization assay, and C albidus keratitis was diagnosed. Despite the identification of C albidus, the clinical condition still worsened due to deep corneal infiltration. After performing intrastromal injection of AB, the corneal infiltration gradually improved.C albidus is a rare cause of diseases in humans and should be considered as a potential pathogen of corneal ulcer. The prognosis of C albidus keratitis will improve if the condition is recognized early and treated properly.
  • |Amphotericin B/*therapeutic use [MESH]
  • |Antifungal Agents/*therapeutic use [MESH]
  • |Cryptococcosis/*diagnosis/*drug therapy [MESH]
  • |Early Diagnosis [MESH]
  • |Humans [MESH]
  • |Keratitis/*diagnosis/*drug therapy/microbiology [MESH]
  • |Male [MESH]


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