Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 253.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 253.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 253.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 253.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 253.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 253.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 253.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\25101985
.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 Medicine+(Baltimore)
2014 ; 93
(7
): e41
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
High body mass index reduces glomerular filtration rate decline in type II
diabetes mellitus patients with stage 3 or 4 chronic kidney disease
#MMPMID25101985
Huang WH
; Chen CY
; Lin JL
; Lin-Tan DT
; Hsu CW
; Yen TH
Medicine (Baltimore)
2014[Aug]; 93
(7
): e41
PMID25101985
show ga
Whether high body mass index (BMI) has an effect on progressive diabetic
nephropathy in type II diabetes mellitus (DM) patients with chronic kidney
disease (CKD) stage 3 or 4 remains unclear. This prospective study aimed to
investigate the relationship between BMI and progression of renal function
deterioration in type II DM patients with CKD stage 3 or 4.A total of 105 type II
DM patients with CKD stage 3 or 4 participated in this 24-month prospective
observational study. Patients were divided into 3 groups according to BMI as
follows: normal group, BMI of 18.5-22.9 kg/m; overweight group, BMI of 23-24.9
kg/m; and obese group, BMI of ?25 kg/m. The primary end point was a 2-fold
elevation in serum creatinine levels (measured twice with a 1-month interval)
from baseline values, need for long-term dialysis, or death during the 24-month
observation period.In the linear regression analysis with the stepwise method,
each 1 kg/m increase in BMI led to an increase of 0.32 mL min × 1.73 m in the
estimated glomerular filtration rate (95% confidence interval, CI, 0.01-0.62; P =
0.04) during the 24-month study period. Moreover, multivariate Cox regression
analysis showed that compared with the obese group, the normal BMI group (hazard
ratio = 2.76, 95% CI : 1.27-6; P = 0.01) achieved the primary outcome after
adjusting for other factors.In this 24-month prospective observational study, we
showed that BMI of ?25 kg/m was a protective factor for renal function
deterioration in type II DM patients with CKD stage 3 or 4.
|*Body Mass Index
[MESH]
|Aged
[MESH]
|Creatinine/blood
[MESH]
|Diabetes Mellitus, Type 2/complications/*physiopathology
[MESH]