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10.1002/bies.201100091 http://scihub22266oqcxt.onion/10.1002/bies.201100091 C4600401!4600401!22006834     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Bioessays 2011 ; 33 (12): 938-45 Nephropedia Template TP {{tp|p=22006834|t=2011. Genome analyses substantiate male mutation bias in many species |pdf=|usr=}}{{22006834}} gab.com Text Genome analyses substantiate male mutation bias in many species JO: Bioessays http://www.kidney.de/pget.php?&tw=1&pmid=22006834 #FOAvip In many species the mutation rate is higher in males than in females, a phenomenon denoted as male mutation bias. This is often observed in animals where males produce many more sperm than females produce eggs, and is thought to result from differences in the number of replication-associated mutations accumulated in each sex. Thus, studies of male mutation bias have the capacity to reveal information about the replication-dependent or replication-independent nature of different mutations. The availability of whole genome sequences for many species, as well as for multiple individuals within a species, has opened the door to studying factors, both sequence-specific and those acting on the genome globally, that affect differences in mutation rates between males and females. Here, we assess the advantages that genomic sequences provide for studies of male mutation bias and general mutation mechanisms, discuss major challenges left unresolved, and speculate about the direction of future studies. Twit Text FOAVip Genome analyses substantiate male mutation bias in many species ????Bioessays http://www.kidney.de/pget.php?&tw=1&pmid=22006834 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=22006834 #FOAvip English Wikipedia <ref>{{Cite pmid|22006834}}</ref> Genome analyses substantiate male mutation bias in many species #MMPMID22006834 Sayres MAW; Makova KD Bioessays 2011[Dec]; 33 (12): 938-45 PMID22006834show ga In many species the mutation rate is higher in males than in females, a phenomenon denoted as male mutation bias. This is often observed in animals where males produce many more sperm than females produce eggs, and is thought to result from differences in the number of replication-associated mutations accumulated in each sex. Thus, studies of male mutation bias have the capacity to reveal information about the replication-dependent or replication-independent nature of different mutations. The availability of whole genome sequences for many species, as well as for multiple individuals within a species, has opened the door to studying factors, both sequence-specific and those acting on the genome globally, that affect differences in mutation rates between males and females. Here, we assess the advantages that genomic sequences provide for studies of male mutation bias and general mutation mechanisms, discuss major challenges left unresolved, and speculate about the direction of future studies. äGenome analyses substantiate male mutation bias in many species (epmc).pdf DeepDyve Pubget Overpricing