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10.1371/journal.pone.0140052 http://scihub22266oqcxt.onion/10.1371/journal.pone.0140052 C4599802!4599802 !26451727     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=26451727 &cmd=llinks): Failed to open stream: HTTP request failed! 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Increased Soluble Urokinase-Type Plasminogen Activator Receptor (suPAR) Levels in Plasma of Suicide Attempters |pdf=|usr=}}{{26451727 }} gab.com Text Increased Soluble Urokinase-Type Plasminogen Activator Receptor (suPAR) Levels in Plasma of Suicide Attempters JO: PLoS One http://www.kidney.de/pget.php?&tw=1&pmid=26451727 #FOAvip The soluble form of the urokinase receptor, suPAR, has been suggested as a novel biomarker of low-grade inflammation. Activation of the immune system has been proposed to contribute to the development of depression and suicidal behavior. In order to identify depressed and suicidal individuals who could benefit from an anti-inflammatory treatment, a reliable biomarker of low-grade inflammation is vital. This study evaluates plasma suPAR levels as a biomarker of low-grade inflammation in patients with major depressive disorder and in patients who recently attempted suicide. The plasma suPAR and an established biomarker, C reactive protein (CRP) of suicide attempters (n = 54), depressed patients (n = 19) and healthy controls (n = 19) was analyzed with enzyme-linked immunosorbent assays. The biomarker attributes of sensitivity and sensibility were evaluated using ROC curve analysis. Both the depressed patients and suicide attempters had increased plasma suPAR. The levels of suPAR discriminated better between controls and suicide attempters than did CRP. In the future, plasma suPAR might be a superior prognosticator regarding outcome of treatment applying conventional antidepressants in conjunction with anti-inflammatory drugs. Twit Text FOAVip Increased Soluble Urokinase-Type Plasminogen Activator Receptor (suPAR) Levels in Plasma of Suicide Attempters ????PLoS One http://www.kidney.de/pget.php?&tw=1&pmid=26451727 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26451727 #FOAvip English Wikipedia <ref>{{Cite pmid|26451727 }}</ref> Increased Soluble Urokinase-Type Plasminogen Activator Receptor (suPAR) Levels in Plasma of Suicide Attempters #MMPMID26451727 Ventorp F ; Gustafsson A ; Träskman-Bendz L ; Westrin Å ; Ljunggren L PLoS One 2015[]; 10 (10 ): e0140052 PMID26451727 show ga The soluble form of the urokinase receptor, suPAR, has been suggested as a novel biomarker of low-grade inflammation. Activation of the immune system has been proposed to contribute to the development of depression and suicidal behavior. In order to identify depressed and suicidal individuals who could benefit from an anti-inflammatory treatment, a reliable biomarker of low-grade inflammation is vital. This study evaluates plasma suPAR levels as a biomarker of low-grade inflammation in patients with major depressive disorder and in patients who recently attempted suicide. The plasma suPAR and an established biomarker, C reactive protein (CRP) of suicide attempters (n = 54), depressed patients (n = 19) and healthy controls (n = 19) was analyzed with enzyme-linked immunosorbent assays. The biomarker attributes of sensitivity and sensibility were evaluated using ROC curve analysis. Both the depressed patients and suicide attempters had increased plasma suPAR. The levels of suPAR discriminated better between controls and suicide attempters than did CRP. In the future, plasma suPAR might be a superior prognosticator regarding outcome of treatment applying conventional antidepressants in conjunction with anti-inflammatory drugs. |*Suicide, Attempted [MESH] |Adult [MESH] |Biomarkers/blood [MESH] |C-Reactive Protein/metabolism [MESH] |Depressive Disorder, Major/blood/*psychology [MESH] |Female [MESH] |Humans [MESH] |Inflammation/blood [MESH] |Male [MESH] |Middle Aged [MESH] |Reactive Oxygen Species/blood [MESH] |Receptors, Urokinase Plasminogen Activator/*blood [MESH] |Solubility [MESH]Increased Soluble Urokinase-Type Plasminogen Activator Receptor (suPAR(epmc).pdf DeepDyve Pubget Overpricing