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10.1038/ncomms9453 http://scihub22266oqcxt.onion/10.1038/ncomms9453 C4598717!4598717 !26419418     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=26419418 &cmd=llinks): Failed to open stream: HTTP request failed! 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Cognitive tutoring induces widespread neuroplasticity and remediates brain function in children with mathematical learning disabilities |pdf=|usr=}}{{26419418 }} gab.com Text Cognitive tutoring induces widespread neuroplasticity and remediates brain function in children with mathematical learning disabilities JO: Nat Commun http://www.kidney.de/pget.php?&tw=1&pmid=26419418 #FOAvip Competency with numbers is essential in today's society; yet, up to 20% of children exhibit moderate to severe mathematical learning disabilities (MLD). Behavioural intervention can be effective, but the neurobiological mechanisms underlying successful intervention are unknown. Here we demonstrate that eight weeks of 1:1 cognitive tutoring not only remediates poor performance in children with MLD, but also induces widespread changes in brain activity. Neuroplasticity manifests as normalization of aberrant functional responses in a distributed network of parietal, prefrontal and ventral temporal-occipital areas that support successful numerical problem solving, and is correlated with performance gains. Remarkably, machine learning algorithms show that brain activity patterns in children with MLD are significantly discriminable from neurotypical peers before, but not after, tutoring, suggesting that behavioural gains are not due to compensatory mechanisms. Our study identifies functional brain mechanisms underlying effective intervention in children with MLD and provides novel metrics for assessing response to intervention. Twit Text FOAVip Cognitive tutoring induces widespread neuroplasticity and remediates brain function in children with mathematical learning disabilities ????Nat Commun http://www.kidney.de/pget.php?&tw=1&pmid=26419418 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26419418 #FOAvip English Wikipedia <ref>{{Cite pmid|26419418 }}</ref> Cognitive tutoring induces widespread neuroplasticity and remediates brain function in children with mathematical learning disabilities #MMPMID26419418 Iuculano T ; Rosenberg-Lee M ; Richardson J ; Tenison C ; Fuchs L ; Supekar K ; Menon V Nat Commun 2015[Sep]; 6 (ä): 8453 PMID26419418 show ga Competency with numbers is essential in today's society; yet, up to 20% of children exhibit moderate to severe mathematical learning disabilities (MLD). Behavioural intervention can be effective, but the neurobiological mechanisms underlying successful intervention are unknown. Here we demonstrate that eight weeks of 1:1 cognitive tutoring not only remediates poor performance in children with MLD, but also induces widespread changes in brain activity. Neuroplasticity manifests as normalization of aberrant functional responses in a distributed network of parietal, prefrontal and ventral temporal-occipital areas that support successful numerical problem solving, and is correlated with performance gains. Remarkably, machine learning algorithms show that brain activity patterns in children with MLD are significantly discriminable from neurotypical peers before, but not after, tutoring, suggesting that behavioural gains are not due to compensatory mechanisms. Our study identifies functional brain mechanisms underlying effective intervention in children with MLD and provides novel metrics for assessing response to intervention. |*Cognition [MESH] |*Neuronal Plasticity [MESH] |Brain/*physiopathology [MESH] |Child [MESH] |Female [MESH] |Humans [MESH] |Learning [MESH] |Learning Disabilities/physiopathology/*psychology/therapy [MESH] |Male [MESH] |Mathematics [MESH]Cognitive tutoring induces widespread neuroplasticity and remediates b(epmc).pdf DeepDyve Pubget Overpricing