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2015 ; 8
(2
): 122-7
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Conflicts of interest in research: looking out for number one means keeping the
primary interest front and center
#MMPMID25851417
Romain PL
Curr Rev Musculoskelet Med
2015[Jun]; 8
(2
): 122-7
PMID25851417
show ga
Conflicts of interest represent circumstances in which professional judgments or
actions regarding a primary interest, such as the responsibilities of a medical
researcher, may be at risk of being unduly influenced by a secondary interest,
such as financial gain or career advancement. The secondary interest may be
financial or non-financial, and the resultant bias may be conscious or
unconscious. The presence of conflicts of interest poses a problem for
professional, patient, and public trust in research and the research enterprise.
Effective means of identifying and managing conflicts are an important element in
successfully achieving the goals of research. These strategies typically focus on
the investigator and rely upon disclosure, which has substantial limitations.
Additional management strategies include process-oriented steps and
outcomes-oriented strategies. More attention to identifying and managing
non-financial conflicts is needed. Future empirical research will be important
for defining which conflicts need to be better addressed and how to achieve this
goal.