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10.1186/s13613-015-0073-9 http://scihub22266oqcxt.onion/10.1186/s13613-015-0073-9 C4596146!4596146 !26445950     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=26445950 &cmd=llinks): Failed to open stream: HTTP request failed! 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Efficacy of chlorhexidine bathing for reducing healthcare associated bloodstream infections: a meta-analysis |pdf=|usr=}}{{26445950 }} gab.com Text Efficacy of chlorhexidine bathing for reducing healthcare associated bloodstream infections: a meta-analysis JO: Ann Intensive Care http://www.kidney.de/pget.php?&tw=1&pmid=26445950 #FOAvip BACKGROUND: We performed a meta-analysis of randomized controlled trials (RCTs) to determine if daily bathing with chlorhexidine decreased hospital-acquired BSIs in critically ill patients. METHODS: We searched the MEDLINE, EMBASE, and Cochrane Central Register of Controlled Trials databases to identify randomized controlled trials that compared daily bathing with chlorhexidine and a control in critically ill patients. RESULTS: This meta-analysis included five RCTs. The overall incidence of measured hospital-acquired BSIs was significantly lower in the chlorhexidine group compared to the controls 0.69 (95 % CI 0.55-0.85; P < 0.001; I (2) = 57.7 %). Gram-positive-induced (RR = 0.49, 95 % CI 0.41-0.58; P = 0.000; I (2) = 0.0 %) bacteremias were significantly less common in the chlorhexidine group. The incidence of MRSA bacteremias (RR 0.63; 95 % CI 0.44-0.91; P = 0.006; I (2) = 30.3 %) was significantly lower among patients who received mupirocin in addition to chlorhexidine bathing than among those who did not routinely receive mupirocin. CONCLUSIONS: Daily bathing with chlorhexidine may be effective to reduce the incidence of hospital-acquired BSIs. However, chlorhexidine bathing alone may be of limited utility in reduction of MRSA bacteremia; intranasal mupirocin may also be required. This meta-analysis has several limitations. Future large-scale international multicenter studies are needed. Twit Text FOAVip Efficacy of chlorhexidine bathing for reducing healthcare associated bloodstream infections: a meta-analysis ????Ann Intensive Care http://www.kidney.de/pget.php?&tw=1&pmid=26445950 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26445950 #FOAvip English Wikipedia <ref>{{Cite pmid|26445950 }}</ref> Efficacy of chlorhexidine bathing for reducing healthcare associated bloodstream infections: a meta-analysis #MMPMID26445950 Choi EY ; Park DA ; Kim HJ ; Park J Ann Intensive Care 2015[Dec]; 5 (1 ): 31 PMID26445950 show ga BACKGROUND: We performed a meta-analysis of randomized controlled trials (RCTs) to determine if daily bathing with chlorhexidine decreased hospital-acquired BSIs in critically ill patients. METHODS: We searched the MEDLINE, EMBASE, and Cochrane Central Register of Controlled Trials databases to identify randomized controlled trials that compared daily bathing with chlorhexidine and a control in critically ill patients. RESULTS: This meta-analysis included five RCTs. The overall incidence of measured hospital-acquired BSIs was significantly lower in the chlorhexidine group compared to the controls 0.69 (95 % CI 0.55-0.85; P < 0.001; I (2) = 57.7 %). Gram-positive-induced (RR = 0.49, 95 % CI 0.41-0.58; P = 0.000; I (2) = 0.0 %) bacteremias were significantly less common in the chlorhexidine group. The incidence of MRSA bacteremias (RR 0.63; 95 % CI 0.44-0.91; P = 0.006; I (2) = 30.3 %) was significantly lower among patients who received mupirocin in addition to chlorhexidine bathing than among those who did not routinely receive mupirocin. CONCLUSIONS: Daily bathing with chlorhexidine may be effective to reduce the incidence of hospital-acquired BSIs. However, chlorhexidine bathing alone may be of limited utility in reduction of MRSA bacteremia; intranasal mupirocin may also be required. This meta-analysis has several limitations. Future large-scale international multicenter studies are needed. äEfficacy of chlorhexidine bathing for reducing healthcare associated b(epmc).pdf DeepDyve Pubget Overpricing