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10.1186/s12915-015-0194-5 http://scihub22266oqcxt.onion/10.1186/s12915-015-0194-5 C4594999!4594999!26437773     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       BMC+Biol 2015 ; 13 (ä): ä Nephropedia Template TP {{tp|p=26437773|t=2015. Archaeal ancestors of eukaryotes: not so elusive any more |pdf=|usr=}}{{26437773}} gab.com Text Archaeal ancestors of eukaryotes: not so elusive any more JO: BMC Biol http://www.kidney.de/pget.php?&tw=1&pmid=26437773 #FOAvip The origin of eukaryotes is one of the hardest problems in evolutionary biology and sometimes raises the ominous specter of irreducible complexity. Reconstruction of the gene repertoire of the last eukaryotic common ancestor (LECA) has revealed a highly complex organism with a variety of advanced features but no detectable evolutionary intermediates to explain their origin. Recently, however, genome analysis of diverse archaea led to the discovery of apparent ancestral versions of several signature eukaryotic systems, such as the actin cytoskeleton and the ubiquitin network, that are scattered among archaea. These findings inspired the hypothesis that the archaeal ancestor of eukaryotes was an unusually complex form with an elaborate intracellular organization. The latest striking discovery made by deep metagenomic sequencing vindicates this hypothesis by showing that in phylogenetic trees eukaryotes fall within a newly identified archaeal group, the Lokiarchaeota, which combine several eukaryotic signatures previously identified in different archaea. The discovery of complex archaea that are the closest living relatives of eukaryotes is most compatible with the symbiogenetic scenario for eukaryogenesis. Twit Text FOAVip Archaeal ancestors of eukaryotes: not so elusive any more ????BMC Biol http://www.kidney.de/pget.php?&tw=1&pmid=26437773 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26437773 #FOAvip English Wikipedia <ref>{{Cite pmid|26437773}}</ref> Archaeal ancestors of eukaryotes: not so elusive any more #MMPMID26437773 Koonin EV BMC Biol 2015[]; 13 (ä): ä PMID26437773show ga The origin of eukaryotes is one of the hardest problems in evolutionary biology and sometimes raises the ominous specter of irreducible complexity. Reconstruction of the gene repertoire of the last eukaryotic common ancestor (LECA) has revealed a highly complex organism with a variety of advanced features but no detectable evolutionary intermediates to explain their origin. Recently, however, genome analysis of diverse archaea led to the discovery of apparent ancestral versions of several signature eukaryotic systems, such as the actin cytoskeleton and the ubiquitin network, that are scattered among archaea. These findings inspired the hypothesis that the archaeal ancestor of eukaryotes was an unusually complex form with an elaborate intracellular organization. The latest striking discovery made by deep metagenomic sequencing vindicates this hypothesis by showing that in phylogenetic trees eukaryotes fall within a newly identified archaeal group, the Lokiarchaeota, which combine several eukaryotic signatures previously identified in different archaea. The discovery of complex archaea that are the closest living relatives of eukaryotes is most compatible with the symbiogenetic scenario for eukaryogenesis. äArchaeal ancestors of eukaryotes: not so elusive any more (epmc).pdf DeepDyve Pubget Overpricing