Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText. Kick-your-searchterm to multiple Engines kick-your-query now !>

A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

10.4161/19336918.2014.994901 http://scihub22266oqcxt.onion/10.4161/19336918.2014.994901 C4594616!4594616!25793575     free     free     free       Cell+Adh+Migr 2015 ; 9 (1-2): 83-9 Nephropedia Template TP {{tp|p=25793575|t=2015. Tenascins in fibrotic disorders?from bench to bedside |pdf=|usr=}}{{25793575}} gab.com Text Tenascins in fibrotic disorders from bench to bedside JO: Cell Adh Migr http://www.kidney.de/pget.php?&tw=1&pmid=25793575 #FOAvip Although fibrosis is becoming increasingly recognized as a major cause of morbidity and mortality in chronic inflammatory diseases, available treatment strategies are limited. Tenascins constitute a family of matricellular proteins, primarily modulating interactions of cells with other matrix components and growth factors. Data obtained from tenascin C deficient mice show important roles of this molecule in several models of fibrosis. Moreover there is growing evidence that tenascin C has a strong impact on chronic inflammation, myofibroblast differentiation and recruitment. Tenascin C as well as tenascin X has furthermore been shown to affect TGF-? activation and signaling. Taken together these data suggest that these proteins might be important factors in fibrosis development and make them attractive both as biological markers and as targets for therapeutical intervention. So far most clinical research in fibrosis has been focused on tenascin C. This review aims at summarizing our up-to-date knowledge on the involvement of tenascin C in the pathogenesis of fibrotic disorders. Twit Text FOAVip Tenascins in fibrotic disorders from bench to bedside ????Cell Adh Migr http://www.kidney.de/pget.php?&tw=1&pmid=25793575 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25793575 #FOAvip English Wikipedia <ref>{{Cite pmid|25793575}}</ref> Tenascins in fibrotic disorders?from bench to bedside #MMPMID25793575 Kasprzycka M; Hammarström C; Haraldsen G Cell Adh Migr 2015[Jan]; 9 (1-2): 83-9 PMID25793575show ga Although fibrosis is becoming increasingly recognized as a major cause of morbidity and mortality in chronic inflammatory diseases, available treatment strategies are limited. Tenascins constitute a family of matricellular proteins, primarily modulating interactions of cells with other matrix components and growth factors. Data obtained from tenascin C deficient mice show important roles of this molecule in several models of fibrosis. Moreover there is growing evidence that tenascin C has a strong impact on chronic inflammation, myofibroblast differentiation and recruitment. Tenascin C as well as tenascin X has furthermore been shown to affect TGF-? activation and signaling. Taken together these data suggest that these proteins might be important factors in fibrosis development and make them attractive both as biological markers and as targets for therapeutical intervention. So far most clinical research in fibrosis has been focused on tenascin C. This review aims at summarizing our up-to-date knowledge on the involvement of tenascin C in the pathogenesis of fibrotic disorders. äTenascins in fibrotic disorders?from bench to bedside (epmc).pdf DeepDyve Pubget Overpricing