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10.1080/19420889.2015.1017176

http://scihub22266oqcxt.onion/10.1080/19420889.2015.1017176
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C4594555!4594555!26479219
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suck abstract from ncbi

pmid26479219      Commun+Integr+Biol 2015 ; 8 (2): ä
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  • A novel role of actomyosin bundles in ERK signaling #MMPMID26479219
  • Hirata H; Sokabe M
  • Commun Integr Biol 2015[Mar]; 8 (2): ä PMID26479219show ga
  • Intracellular and extracellular mechanical environments have a significant impact on survival and proliferation of cells. While the extracellular signal-regulated kinase (ERK) subfamily of MAP kinases plays critical roles in regulations of these cellular behaviors, activation of ERK is affected by mechanical conditions of cells. We have recently found that ERK is activated on contractile actomyosin bundles. ERK activation on actomyosin bundles depends on tension in the bundles, which is generated by either myosin II activity of external forces. In this Addendum, we discuss a novel, potential role of actomyosin bundles in ERK signaling and mechanical regulation of cell survival and proliferation.
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