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10.4161/19336918.2014.972740 http://scihub22266oqcxt.onion/10.4161/19336918.2014.972740 C4594335!4594335!25482617     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Cell+Adh+Migr 2014 ; 8 (6): 578-87 Nephropedia Template TP {{tp|p=25482617|t=2014. SLUG: Critical regulator of epithelial cell identity in breast development and cancer |pdf=|usr=}}{{25482617}} gab.com Text SLUG: Critical regulator of epithelial cell identity in breast development and cancer JO: Cell Adh Migr http://www.kidney.de/pget.php?&tw=1&pmid=25482617 #FOAvip SLUG, a member of the SNAIL family of transcriptional repressors, is known to play a diverse number of roles in the cell, and its deregulation has been observed in a variety of cancers including breast. Here, we focus on SLUG's role as a master regulator of mammary epithelial cell (MEC) fate and lineage commitment in the normal mammary gland, and discuss how aberrant SLUG expression can influence breast tumor formation, phenotype, and progression. Specifically, we discuss SLUG's involvement in MEC differentiation, stemness, cellular plasticity, and the epithelial to mesenchymal transition (EMT), and highlight the complex connection between these programs during development and disease progression. Undoubtedly, delineating how molecular factors influence lineage identity and cell-state dynamics in the normal mammary gland will contribute to our understanding of breast tumor heterogeneity. Twit Text FOAVip SLUG: Critical regulator of epithelial cell identity in breast development and cancer ????Cell Adh Migr http://www.kidney.de/pget.php?&tw=1&pmid=25482617 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25482617 #FOAvip English Wikipedia <ref>{{Cite pmid|25482617}}</ref> SLUG: Critical regulator of epithelial cell identity in breast development and cancer #MMPMID25482617 Phillips S; Kuperwasser C Cell Adh Migr 2014[Nov]; 8 (6): 578-87 PMID25482617show ga SLUG, a member of the SNAIL family of transcriptional repressors, is known to play a diverse number of roles in the cell, and its deregulation has been observed in a variety of cancers including breast. Here, we focus on SLUG's role as a master regulator of mammary epithelial cell (MEC) fate and lineage commitment in the normal mammary gland, and discuss how aberrant SLUG expression can influence breast tumor formation, phenotype, and progression. Specifically, we discuss SLUG's involvement in MEC differentiation, stemness, cellular plasticity, and the epithelial to mesenchymal transition (EMT), and highlight the complex connection between these programs during development and disease progression. Undoubtedly, delineating how molecular factors influence lineage identity and cell-state dynamics in the normal mammary gland will contribute to our understanding of breast tumor heterogeneity. äSLUG: Critical regulator of epithelial cell identity in breast develop(epmc).pdf DeepDyve Pubget Overpricing