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10.1098/rsob.150093 http://scihub22266oqcxt.onion/10.1098/rsob.150093 C4593667!4593667 !26333836     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\26333836 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Open+Biol 2015 ; 5 (9 ): 150093 Nephropedia Template TP {{tp|p=26333836 |t=2015. Cell cycle progression is an essential regulatory component of phospholipid metabolism and membrane homeostasis |pdf=|usr=}}{{26333836 }} gab.com Text Cell cycle progression is an essential regulatory component of phospholipid metabolism and membrane homeostasis JO: Open Biol http://www.kidney.de/pget.php?&tw=1&pmid=26333836 #FOAvip We show that phospholipid anabolism does not occur uniformly during the metazoan cell cycle. Transition to S-phase is required for optimal mobilization of lipid precursors, synthesis of specific phospholipid species and endoplasmic reticulum (ER) homeostasis. Average changes observed in whole-cell phospholipid composition, and total ER lipid content, upon stimulation of cell growth can be explained by the cell cycle distribution of the population. TORC1 promotes phospholipid anabolism by slowing S/G2 progression. The cell cycle stage-specific nature of lipid biogenesis is dependent on p53. We propose that coupling lipid metabolism to cell cycle progression is a means by which cells have evolved to coordinate proliferation with cell and organelle growth. Twit Text FOAVip Cell cycle progression is an essential regulatory component of phospholipid metabolism and membrane homeostasis ????Open Biol http://www.kidney.de/pget.php?&tw=1&pmid=26333836 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26333836 #FOAvip English Wikipedia <ref>{{Cite pmid|26333836 }}</ref> Cell cycle progression is an essential regulatory component of phospholipid metabolism and membrane homeostasis #MMPMID26333836 Sanchez-Alvarez M ; Zhang Q ; Finger F ; Wakelam MJ ; Bakal C Open Biol 2015[Sep]; 5 (9 ): 150093 PMID26333836 show ga We show that phospholipid anabolism does not occur uniformly during the metazoan cell cycle. Transition to S-phase is required for optimal mobilization of lipid precursors, synthesis of specific phospholipid species and endoplasmic reticulum (ER) homeostasis. Average changes observed in whole-cell phospholipid composition, and total ER lipid content, upon stimulation of cell growth can be explained by the cell cycle distribution of the population. TORC1 promotes phospholipid anabolism by slowing S/G2 progression. The cell cycle stage-specific nature of lipid biogenesis is dependent on p53. We propose that coupling lipid metabolism to cell cycle progression is a means by which cells have evolved to coordinate proliferation with cell and organelle growth. |Animals [MESH] |Cell Cycle/*physiology [MESH] |Drosophila Proteins/antagonists & inhibitors/genetics/metabolism [MESH] |Drosophila/metabolism [MESH] |Endoplasmic Reticulum Stress/drug effects [MESH] |Endoplasmic Reticulum/*metabolism [MESH] |G2 Phase Cell Cycle Checkpoints/drug effects [MESH] |Insulin/pharmacology [MESH] |Lipid Metabolism/*physiology [MESH] |Mechanistic Target of Rapamycin Complex 1 [MESH] |Multiprotein Complexes/metabolism [MESH] |Phosphatidylcholines/metabolism [MESH] |Phosphatidylethanolamines/metabolism [MESH] |RNA Interference [MESH] |RNA, Small Interfering/metabolism [MESH] |S Phase Cell Cycle Checkpoints/drug effects [MESH] |Sterol Regulatory Element Binding Proteins/genetics/metabolism [MESH] |TOR Serine-Threonine Kinases/metabolism [MESH] |Thymidine/pharmacology [MESH]Cell cycle progression is an essential regulatory component of phospho(epmc).pdf DeepDyve Pubget Overpricing