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10.1097/HP.0000000000000356 http://scihub22266oqcxt.onion/10.1097/HP.0000000000000356 C4593311!4593311!26425901     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Health+Phys 2015 ; 109 (5): 399-413 Nephropedia Template TP {{tp|p=26425901|t=2015. The Delayed Effects of Acute Radiation Syndrome: Evidence of long-term functional changes in the clonogenic cells of the small intestine |pdf=|usr=}}{{26425901}} gab.com Text The Delayed Effects of Acute Radiation Syndrome: Evidence of long-term functional changes in the clonogenic cells of the small intestine JO: Health Phys http://www.kidney.de/pget.php?&tw=1&pmid=26425901 #FOAvip Long term or residual damage post-irradiation has been described for many tissues. In hematopoietic stem cells (HSC) this is only revealed when the HSC are stressed and required to regenerate and repopulate a myeloablated host. Such an assay cannot be used to assess the recovery potential of previously irradiated intestinal stem cells (ISC) due to their incompatibility with transplantation. The best approximation to the HSC assay is the crypt microcolony assay, also based on clonogen survival. In the current study the regenerative capacity of intestinal clonogenic cells in mice that had survived 13 Gy irradiation (with 5% bone marrow shielding to allow survival through the hematopoietic syndrome) and were then aged for 200 days, was compared to previously unirradiated age matched controls. Interestingly, at 200 days following 13 Gy there remained a statistically significant reduction in crypts present in the various small intestinal regions (illustrating that the gastrointestinal epithelium had not fully recovered despite the 200 day interval). However, upon re-irradiation on day 196, those mice previously irradiated had improved crypt survival and regeneration compared to the age matched controls. This was evident in all regions of the small intestine following 11?13 Gy re-exposure. Thus, there were either more clonogens per crypt within those previously irradiated and/or those that were present were more radioresistant (possibly because a subpopulation was more quiescent). This is contrary to the popular belief that previously irradiated animals may have an impaired/delayed regenerative response and be more radiosensitive. Twit Text FOAVip The Delayed Effects of Acute Radiation Syndrome: Evidence of long-term functional changes in the clonogenic cells of the small intestine ????Health Phys http://www.kidney.de/pget.php?&tw=1&pmid=26425901 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26425901 #FOAvip English Wikipedia <ref>{{Cite pmid|26425901}}</ref> The Delayed Effects of Acute Radiation Syndrome: Evidence of long-term functional changes in the clonogenic cells of the small intestine #MMPMID26425901 Booth C; Tudor GL; Katz BP; MacVittie TJ Health Phys 2015[Nov]; 109 (5): 399-413 PMID26425901show ga Long term or residual damage post-irradiation has been described for many tissues. In hematopoietic stem cells (HSC) this is only revealed when the HSC are stressed and required to regenerate and repopulate a myeloablated host. Such an assay cannot be used to assess the recovery potential of previously irradiated intestinal stem cells (ISC) due to their incompatibility with transplantation. The best approximation to the HSC assay is the crypt microcolony assay, also based on clonogen survival. In the current study the regenerative capacity of intestinal clonogenic cells in mice that had survived 13 Gy irradiation (with 5% bone marrow shielding to allow survival through the hematopoietic syndrome) and were then aged for 200 days, was compared to previously unirradiated age matched controls. Interestingly, at 200 days following 13 Gy there remained a statistically significant reduction in crypts present in the various small intestinal regions (illustrating that the gastrointestinal epithelium had not fully recovered despite the 200 day interval). However, upon re-irradiation on day 196, those mice previously irradiated had improved crypt survival and regeneration compared to the age matched controls. This was evident in all regions of the small intestine following 11?13 Gy re-exposure. Thus, there were either more clonogens per crypt within those previously irradiated and/or those that were present were more radioresistant (possibly because a subpopulation was more quiescent). This is contrary to the popular belief that previously irradiated animals may have an impaired/delayed regenerative response and be more radiosensitive. äThe Delayed Effects of Acute Radiation Syndrome: Evidence of long-term(epmc).pdf DeepDyve Pubget Overpricing