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10.1152/ajpheart.00259.2015

http://scihub22266oqcxt.onion/10.1152/ajpheart.00259.2015
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C4591409!4591409!26254330
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suck abstract from ncbi


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pmid26254330      Am+J+Physiol+Heart+Circ+Physiol 2015 ; 309 (5): H926-34
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  • ?-Lipoic acid reduces neurogenic hypertension by blunting oxidative stress-mediated increase in ADAM17 #MMPMID26254330
  • de Queiroz TM; Xia H; Filipeanu CM; Braga VA; Lazartigues E
  • Am J Physiol Heart Circ Physiol 2015[Sep]; 309 (5): H926-34 PMID26254330show ga
  • This study highlights the relationship between type 2 angiotensin-converting enzyme and metalloprotease 17 (ADAM17) in hypertension, emphasizing the role of oxidative stress as a mediator between the type 1 ANG II receptor and ADAM17 in the mouse brain. Furthermore, our study shows the benefits of lipoic acid treatment in preventing ADAM17 upregulation and thus the development of hypertension.
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