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2015 ; 5
(ä): 14562
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English Wikipedia
Detailed classification of swimming paths in the Morris Water Maze: multiple
strategies within one trial
#MMPMID26423140
Gehring TV
; Luksys G
; Sandi C
; Vasilaki E
Sci Rep
2015[Oct]; 5
(ä): 14562
PMID26423140
show ga
The Morris Water Maze is a widely used task in studies of spatial learning with
rodents. Classical performance measures of animals in the Morris Water Maze
include the escape latency, and the cumulative distance to the platform. Other
methods focus on classifying trajectory patterns to stereotypical classes
representing different animal strategies. However, these approaches typically
consider trajectories as a whole, and as a consequence they assign one full
trajectory to one class, whereas animals often switch between these strategies,
and their corresponding classes, within a single trial. To this end, we take a
different approach: we look for segments of diverse animal behaviour within one
trial and employ a semi-automated classification method for identifying the
various strategies exhibited by the animals within a trial. Our method allows us
to reveal significant and systematic differences in the exploration strategies of
two animal groups (stressed, non-stressed), that would be unobserved by earlier
methods.