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10.1080/2162402X.2015.1029704

http://scihub22266oqcxt.onion/10.1080/2162402X.2015.1029704
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C4589064!4589064!26451298
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suck abstract from ncbi


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pmid26451298      Oncoimmunology 2015 ; 4 (10): ä
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  • Innate vs Adaptive: PD-L1-mediated immune resistance by melanoma #MMPMID26451298
  • Berry S; Taube JM
  • Oncoimmunology 2015[Oct]; 4 (10): ä PMID26451298show ga
  • Oncogenic driver mutations in several tumor types promote constitutive PD-L1 expression, a crucial ligand in PD-1-mediated tumor immune escape. Our studies in melanoma suggest a different mechanism?one of ?adaptive immune resistance? in which PD-L1 expression is primarily driven by cytokine induction and is independent of BRAF mutational status.
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