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10.1186/s13046-015-0224-8 http://scihub22266oqcxt.onion/10.1186/s13046-015-0224-8 C4588898!4588898!26419932     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Exp+Clin+Cancer+Res 2015 ; 34 (ä): ä Nephropedia Template TP {{tp|p=26419932|t=2015. miR-96 suppresses renal cell carcinoma invasion via downregulation of Ezrin expression |pdf=|usr=}}{{26419932}} gab.com Text miR-96 suppresses renal cell carcinoma invasion via downregulation of Ezrin expression JO: J Exp Clin Cancer Res http://www.kidney.de/pget.php?&tw=1&pmid=26419932 #FOAvip Background: The present study examined the role of microRNA (miR)-96 in renal cell carcinoma (RCC) invasion. Methods: The expression of miR-96 was detected by quantitative reverse transcription-polymerase chain reaction in human RCC cell lines with high (Caki-1) and low (786-O) metastatic potential. Invasive ability and Ezrin expression were assessed in Caki-1 and 786-O cells transfected with a miR-96 mimic or inhibitor using wound healing assays, Transwell assays and western blotting. Expression of miR-96 and Ezrin was also examined in primary RCC samples from 17 patients with metastatic disease and 46 patients who maintained remission during a follow-up period of 37 months. Results: miR-96 expression was significantly lower in Caki-1compared to786-O cells. The invasive ability of Caki-1 and 786-O cells increased following transfection of cells with miR-96 inhibitor, whereas it decreased following transfection with miR-96 mimic. Ezrin levels were negatively correlated with miR-96 in RCC, and inhibition of Ezrin expression suppressed the miR-96-induced change in invasive ability. The negative correlation between miR-96 and metastasis/Ezrin expression was also observed in human RCC specimens. Conclusions: These results suggest that miR-96 suppresses RCC invasion by modulating Ezrin expression. Twit Text FOAVip miR-96 suppresses renal cell carcinoma invasion via downregulation of Ezrin expression ????J Exp Clin Cancer Res http://www.kidney.de/pget.php?&tw=1&pmid=26419932 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26419932 #FOAvip English Wikipedia <ref>{{Cite pmid|26419932}}</ref> miR-96 suppresses renal cell carcinoma invasion via downregulation of Ezrin expression #MMPMID26419932 Yu N; Fu S; Liu Y; Xu Z; Liu Y; Hao J; Wang B; Zhang A J Exp Clin Cancer Res 2015[]; 34 (ä): ä PMID26419932show ga Background: The present study examined the role of microRNA (miR)-96 in renal cell carcinoma (RCC) invasion. Methods: The expression of miR-96 was detected by quantitative reverse transcription-polymerase chain reaction in human RCC cell lines with high (Caki-1) and low (786-O) metastatic potential. Invasive ability and Ezrin expression were assessed in Caki-1 and 786-O cells transfected with a miR-96 mimic or inhibitor using wound healing assays, Transwell assays and western blotting. Expression of miR-96 and Ezrin was also examined in primary RCC samples from 17 patients with metastatic disease and 46 patients who maintained remission during a follow-up period of 37 months. Results: miR-96 expression was significantly lower in Caki-1compared to786-O cells. The invasive ability of Caki-1 and 786-O cells increased following transfection of cells with miR-96 inhibitor, whereas it decreased following transfection with miR-96 mimic. Ezrin levels were negatively correlated with miR-96 in RCC, and inhibition of Ezrin expression suppressed the miR-96-induced change in invasive ability. The negative correlation between miR-96 and metastasis/Ezrin expression was also observed in human RCC specimens. Conclusions: These results suggest that miR-96 suppresses RCC invasion by modulating Ezrin expression. ämiR-96 suppresses renal cell carcinoma invasion via downregulation of (epmc).pdf DeepDyve Pubget Overpricing