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2015 ; 7
(9
): 7749-63
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gab.com Text
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English Wikipedia
Milk Consumption and Mortality from All Causes, Cardiovascular Disease, and
Cancer: A Systematic Review and Meta-Analysis
#MMPMID26378576
Larsson SC
; Crippa A
; Orsini N
; Wolk A
; Michaëlsson K
Nutrients
2015[Sep]; 7
(9
): 7749-63
PMID26378576
show ga
Results from epidemiological studies of milk consumption and mortality are
inconsistent. We conducted a systematic review and meta-analysis of prospective
studies assessing the association of non-fermented and fermented milk consumption
with mortality from all causes, cardiovascular disease, and cancer. PubMed was
searched until August 2015. A two-stage, random-effects, dose-response
meta-analysis was used to combine study-specific results. Heterogeneity among
studies was assessed with the I² statistic. During follow-up periods ranging from
4.1 to 25 years, 70,743 deaths occurred among 367,505 participants. The range of
non-fermented and fermented milk consumption and the shape of the associations
between milk consumption and mortality differed considerably between studies.
There was substantial heterogeneity among studies of non-fermented milk
consumption in relation to mortality from all causes (12 studies; I² = 94%),
cardiovascular disease (five studies; I² = 93%), and cancer (four studies; I² =
75%) as well as among studies of fermented milk consumption and all-cause
mortality (seven studies; I² = 88%). Thus, estimating pooled hazard ratios was
not appropriate. Heterogeneity among studies was observed in most subgroups
defined by sex, country, and study quality. In conclusion, we observed no
consistent association between milk consumption and all-cause or cause-specific
mortality.
|*Diet/adverse effects
[MESH]
|*Feeding Behavior
[MESH]
|*Milk/adverse effects
[MESH]
|Adult
[MESH]
|Aged
[MESH]
|Animals
[MESH]
|Cardiovascular Diseases/diagnosis/*mortality/prevention & control
[MESH]
|Cultured Milk Products/adverse effects
[MESH]
|Female
[MESH]
|Humans
[MESH]
|Male
[MESH]
|Middle Aged
[MESH]
|Neoplasms/diagnosis/*mortality/prevention & control
[MESH]