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Non-operative anti-caries agents and dental caries increment among adults at high
caries risk: a retrospective cohort study
#MMPMID26403525
Chaffee BW
; Cheng J
; Featherstone JD
BMC Oral Health
2015[Sep]; 15
(1
): 111
PMID26403525
show ga
BACKGROUND: Consensus guidelines support non-operative preventives for dental
caries management; yet, their use in practice is far from universal. The purpose
of this study was to evaluate the effectiveness of non-operative anti-caries
agents in caries prevention among high caries risk adults at a university clinic
where risk-based caries management is emphasized. METHODS: This retrospective
observational study drew data from the electronic patient records of
non-edentulous adult patients deemed to be at high risk for dental caries during
baseline oral evaluations that were completed between July 1, 2007 and December
31, 2012 at a dental university in the United States. We calculated and compared
adjusted mean estimates for the number of new decayed or restored teeth (DFT
increment) from baseline to the next completed oral evaluation (N?=?2,724
patients with follow-up) across three categories of delivery of non-operative
anti-caries agents (e.g., high-concentration fluoride toothpaste, chlorhexidine
rinse, xylitol products): never, at a single appointment, or at ?2 appointments
?4 weeks apart. Estimates were adjusted for patient and provider characteristics,
baseline dental status, losses-to-follow-up, and follow-up time. RESULTS:
Approximately half the patients did not receive any form of non-operative
anti-caries agent. Most that received anti-caries agents were given more than one
type of product in combination. One-time delivery of anti-caries agents was
associated with a similar DFT increment as receiving no such therapy (difference
in increment: -0.04; 95% CI: -0.28, 0.21). However, repeated, spaced delivery of
anti-caries agents was associated with approximately one decayed or restored
tooth prevented over 18 months for every three patients treated (difference in
increment: -0.35; 95% CI: -0.65, -0.08). CONCLUSIONS: These results lend evidence
that repeatedly receiving anti-caries agents can reduce tooth decay among
high-risk patients engaged in regular dental care.
|*Dental Caries Susceptibility
[MESH]
|Adolescent
[MESH]
|Adult
[MESH]
|Aged
[MESH]
|Aged, 80 and over
[MESH]
|Anti-Infective Agents, Local/therapeutic use
[MESH]
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