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Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Clin+Kidney+J 2015 ; 8 (5): 492-502 Nephropedia Template TP
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Unmet medical needs in lupus nephritis: solutions through evidence-based, personalized medicine #MMPMID26413272
Anders HJ; Weidenbusch M; Rovin B
Clin Kidney J 2015[Oct]; 8 (5): 492-502 PMID26413272show ga
Lupus nephritis (LN) remains a kidney disease with significant unmet medical needs despite extensive clinical and translational research over the past decade. These include the need to (i) predict the individual risk for LN in a patient with systemic lupus erythematosus, (ii) identify the best therapeutic option for an individual patient, (iii) distinguish chronic kidney damage from active immunologic kidney injury, (iv) develop efficient treatments with acceptable or no side effects and improve the design of randomized clinical trials so that effective drugs demonstrate efficacy. This review discusses the underlying reasons for these unmet medical needs and options of how to overcome them in the future.