Right on TARGET: glutamine metabolism in cancer #MMPMID26425657
Ratnikov B; Jeon YJ; Smith JW; Ronai ZA
Oncoscience 2015[]; 2 (8): 681-3 PMID26425657show ga
Recent studies highlight the importance of glutamine metabolism in metabolic reprogramming, which underlies cancer cell addiction to glutamine. Examples for the dependence on glutamine metabolism are seen across different tumor types as during different phases of cancer development, progression and response to therapy. In this perspective, we assess the possibility of targeting glutamine metabolism as a therapeutic modality for cancer.