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10.15557/JoU.2015.0001 http://scihub22266oqcxt.onion/10.15557/JoU.2015.0001 C4579708!4579708!26675385     free     free     free Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Ultrason 2015 ; 15 (60): 5-14 Nephropedia Template TP {{tp|p=26675385|t=2015. New aspects in shear-wave elastography of prostate cancer |pdf=|usr=}}{{26675385}} gab.com Text New aspects in shear-wave elastography of prostate cancer JO: J Ultrason http://www.kidney.de/pget.php?&tw=1&pmid=26675385 #FOAvip Aim: This study was designed to evaluate the performance of shear-wave elastography as a diagnostic tool for prostate cancer in a larger cohort of patients than previously reported. Patients and methods: Seventy-three patients with suspected prostate carcinoma were investigated by ultrasound elastography followed by directed biopsy. The elastographic and histological results for all biopsies were compared. Results: After exclusion of invalid and non-assessable results, 794 samples were obtained for which both a histological assessment and an elastometric result (tissue stiffness in kPa) were available: according to the histology 589 were benign and 205 were malignant. Tissue elasticity was found to be weakly correlated with patient's age, PSA level and gland volume. ROC analysis showed that, for the set of results acquired, elastometry did not fulfil literature claims that it could identify malignant neoplasia with high sensitivity and specificity. However, it did show promise in distinguishing between Gleason scores ?6 and >6 when malignancy had already been identified. Unexpected observations were the finding of a smaller proportion of tumours in the lateral regions of the prostate than generally expected, and also the observation that the elasticity of benign prostate tissue is region-sensitive, the tissue being stiffest in the basal region and more elastic at the apex. Conclusions: Shear-wave elastography was found to be a poor predictor of malignancy, but for malignant lesions an elasticity cut-off of 80 kPa allowed a fairly reliable distinction between lesions with Gleason ?6 and those with Gleason >6. We demonstrate an increase in elasticity of benign prostate tissue from the basal to the apical region. Twit Text FOAVip New aspects in shear-wave elastography of prostate cancer ????J Ultrason http://www.kidney.de/pget.php?&tw=1&pmid=26675385 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26675385 #FOAvip English Wikipedia <ref>{{Cite pmid|26675385}}</ref> New aspects in shear-wave elastography of prostate cancer #MMPMID26675385 Porsch M; Wendler JJ; Liehr UB; Lux A; Schostak M; Pech M J Ultrason 2015[Mar]; 15 (60): 5-14 PMID26675385show ga Aim: This study was designed to evaluate the performance of shear-wave elastography as a diagnostic tool for prostate cancer in a larger cohort of patients than previously reported. Patients and methods: Seventy-three patients with suspected prostate carcinoma were investigated by ultrasound elastography followed by directed biopsy. The elastographic and histological results for all biopsies were compared. Results: After exclusion of invalid and non-assessable results, 794 samples were obtained for which both a histological assessment and an elastometric result (tissue stiffness in kPa) were available: according to the histology 589 were benign and 205 were malignant. Tissue elasticity was found to be weakly correlated with patient's age, PSA level and gland volume. ROC analysis showed that, for the set of results acquired, elastometry did not fulfil literature claims that it could identify malignant neoplasia with high sensitivity and specificity. However, it did show promise in distinguishing between Gleason scores ?6 and >6 when malignancy had already been identified. Unexpected observations were the finding of a smaller proportion of tumours in the lateral regions of the prostate than generally expected, and also the observation that the elasticity of benign prostate tissue is region-sensitive, the tissue being stiffest in the basal region and more elastic at the apex. Conclusions: Shear-wave elastography was found to be a poor predictor of malignancy, but for malignant lesions an elasticity cut-off of 80 kPa allowed a fairly reliable distinction between lesions with Gleason ?6 and those with Gleason >6. We demonstrate an increase in elasticity of benign prostate tissue from the basal to the apical region. äNew aspects in shear-wave elastography of prostate cancer (epmc).pdf DeepDyve Pubget Overpricing