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10.5483/BMBRep.2015.48.5.008 http://scihub22266oqcxt.onion/10.5483/BMBRep.2015.48.5.008 C4578570!4578570!25748171     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       BMB+Rep 2015 ; 48 (5): 295-300 Nephropedia Template TP {{tp|p=25748171|t=2015. Adrenergic receptor ?2 activation by stress promotes breast cancer progression through macrophages M2 polarization in tumor microenvironment |pdf=|usr=}}{{25748171}} gab.com Text Adrenergic receptor 2 activation by stress promotes breast cancer progression through macrophages M2 polarization in tumor microenvironment JO: BMB Rep http://www.kidney.de/pget.php?&tw=1&pmid=25748171 #FOAvip Stress and its related hormones epinephrine (E) and norepinephrine (NE) play a crucial role in tumor progression. Macrophages in the tumor microenvironment (TME) polarized to M2 is also a vital pathway for tumor deterioration. Here, we explore the underlying role of macrophages in the effect of stress and E promoting breast cancer growth. It was found that the weight and volume of tumor in tumor bearing mice were increased, and dramatically accompanied with the rising E level after chronic stress using social isolation. What is most noteworthy, the number of M2 macrophages inside tumor was up-regulated with it. The effects of E treatment appear to be directly related to the change of M2 phenotype is reproduced in vitro. Moreover, E receptor ADR?2 involved in E promoting M2 polarization was comprehended simultaneously. Our results imply psychological stress is influential on specific immune system, more essential for the comprehensive treatment against tumors. [BMB Reports 2015; 48(5): 295-300] Twit Text FOAVip Adrenergic receptor 2 activation by stress promotes breast cancer progression through macrophages M2 polarization in tumor microenvironment ????BMB Rep http://www.kidney.de/pget.php?&tw=1&pmid=25748171 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25748171 #FOAvip English Wikipedia <ref>{{Cite pmid|25748171}}</ref> Adrenergic receptor ?2 activation by stress promotes breast cancer progression through macrophages M2 polarization in tumor microenvironment #MMPMID25748171 Qin Jf; Jin Fj; Li N; Guan Ht; Lan L; Ni H; Wang Y BMB Rep 2015[May]; 48 (5): 295-300 PMID25748171show ga Stress and its related hormones epinephrine (E) and norepinephrine (NE) play a crucial role in tumor progression. Macrophages in the tumor microenvironment (TME) polarized to M2 is also a vital pathway for tumor deterioration. Here, we explore the underlying role of macrophages in the effect of stress and E promoting breast cancer growth. It was found that the weight and volume of tumor in tumor bearing mice were increased, and dramatically accompanied with the rising E level after chronic stress using social isolation. What is most noteworthy, the number of M2 macrophages inside tumor was up-regulated with it. The effects of E treatment appear to be directly related to the change of M2 phenotype is reproduced in vitro. Moreover, E receptor ADR?2 involved in E promoting M2 polarization was comprehended simultaneously. Our results imply psychological stress is influential on specific immune system, more essential for the comprehensive treatment against tumors. [BMB Reports 2015; 48(5): 295-300] äAdrenergic receptor ?2 activation by stress promotes breast cancer pro(epmc).pdf DeepDyve Pubget Overpricing