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10.1084/jem.20150165

http://scihub22266oqcxt.onion/10.1084/jem.20150165
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C4577837!4577837!26347470
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suck abstract from ncbi


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pmid26347470      J+Exp+Med 2015 ; 212 (10): 1529-49
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  • Brain endothelial TAK1 and NEMO safeguard the neurovascular unit #MMPMID26347470
  • Ridder DA; Wenzel J; Müller K; Töllner K; Tong XK; Assmann JC; Stroobants S; Weber T; Niturad C; Fischer L; Lembrich B; Wolburg H; Grand?Maison M; Papadopoulos P; Korpos E; Truchetet F; Rades D; Sorokin LM; Schmidt-Supprian M; Bedell BJ; Pasparakis M; Balschun D; D?Hooge R; Löscher W; Hamel E; Schwaninger M
  • J Exp Med 2015[Sep]; 212 (10): 1529-49 PMID26347470show ga
  • Ridder et al. show that deletion of NEMO, a component of NF-kB signaling, in brain endothelial cells results in increased cerebral vascular permeability and endothelial cell death, and recapitulates the neurological symptoms observed in the genetic disease incontinentia pigmenti.
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