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10.1503/cmaj.141608

http://scihub22266oqcxt.onion/10.1503/cmaj.141608
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suck abstract from ncbi


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pmid26216608
      CMAJ 2015 ; 187 (13 ): 961-969
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  • Effect of nasal balloon autoinflation in children with otitis media with effusion in primary care: an open randomized controlled trial #MMPMID26216608
  • Williamson I ; Vennik J ; Harnden A ; Voysey M ; Perera R ; Kelly S ; Yao G ; Raftery J ; Mant D ; Little P
  • CMAJ 2015[Sep]; 187 (13 ): 961-969 PMID26216608 show ga
  • BACKGROUND: Otitis media with effusion is a common problem that lacks an evidence-based nonsurgical treatment option. We assessed the clinical effectiveness of treatment with a nasal balloon device in a primary care setting. METHODS: We conducted an open, pragmatic randomized controlled trial set in 43 family practices in the United Kingdom. Children aged 4-11 years with a recent history of ear symptoms and otitis media with effusion in 1 or both ears, confirmed by tympanometry, were allocated to receive either autoinflation 3 times daily for 1-3 months plus usual care or usual care alone. Clearance of middle-ear fluid at 1 and 3 months was assessed by experts masked to allocation. RESULTS: Of 320 children enrolled, those receiving autoinflation were more likely than controls to have normal tympanograms at 1 month (47.3% [62/131] v. 35.6% [47/132]; adjusted relative risk [RR] 1.36, 95% confidence interval [CI] 0.99 to 1.88) and at 3 months (49.6% [62/125] v. 38.3% [46/120]; adjusted RR 1.37, 95% CI 1.03 to 1.83; number needed to treat = 9). Autoinflation produced greater improvements in ear-related quality of life (adjusted between-group difference in change from baseline in OMQ-14 [an ear-related measure of quality of life] score -0.42, 95% CI -0.63 to -0.22). Compliance was 89% at 1 month and 80% at 3 months. Adverse events were mild, infrequent and comparable between groups. INTERPRETATION: Autoinflation in children aged 4-11 years with otitis media with effusion is feasible in primary care and effective both in clearing effusions and improving symptoms and ear-related child and parent quality of life. TRIAL REGISTRATION: ISRCTN, No. 55208702.
  • |Child [MESH]
  • |Child, Preschool [MESH]
  • |Family Practice [MESH]
  • |Female [MESH]
  • |Humans [MESH]
  • |Logistic Models [MESH]
  • |Male [MESH]
  • |Otitis Media with Effusion/*therapy [MESH]
  • |Primary Health Care/*methods [MESH]
  • |Quality of Life [MESH]


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