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10.1002/mus.24495 http://scihub22266oqcxt.onion/10.1002/mus.24495 C4577279!4577279 !25363903     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\25363903 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Muscle+Nerve 2015 ; 51 (3 ): 449-54 Nephropedia Template TP {{tp|p=25363903 |t=2015. Progressive polyradiculoneuropathy due to intraneural oxalate deposition in type 1 primary hyperoxaluria |pdf=|usr=}}{{25363903 }} gab.com Text Progressive polyradiculoneuropathy due to intraneural oxalate deposition in type 1 primary hyperoxaluria JO: Muscle Nerve http://www.kidney.de/pget.php?&tw=1&pmid=25363903 #FOAvip INTRODUCTION: A 24-year-old man with primary hyperoxaluria type 1 (PH1) presented with a rapidly progressive axonal and demyelinating sensorimotor polyradiculoneuropathy shortly after the onset of end-stage renal disease. His plasma oxalate level was markedly elevated at 107 µmol/L (normal<1.8 µmol/L). METHODS: A sural nerve biopsy was performed. Teased fiber and paraffin and epoxy sections were done and morphometric procedures were performed on this sample and on an archived sample from a 22-year-old man as an age- and gender-matched control. Embedded teased fiber electron microscopy was also performed. RESULTS: The biopsy revealed secondary demyelination and axonal degeneration. Under polarized light, multiple bright hexagonal, rectangular, and starburst inclusions, typical of calcium oxalate monohydrate crystals, were seen. CONCLUSIONS: The proposed mechanisms of nerve damage include disruption of axonal transport due to crystal deposition, toxic effect of oxalate, or nerve ischemia related to vessel occlusion from oxalate crystal deposition. Twit Text FOAVip Progressive polyradiculoneuropathy due to intraneural oxalate deposition in type 1 primary hyperoxaluria ????Muscle Nerve http://www.kidney.de/pget.php?&tw=1&pmid=25363903 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25363903 #FOAvip English Wikipedia <ref>{{Cite pmid|25363903 }}</ref> Progressive polyradiculoneuropathy due to intraneural oxalate deposition in type 1 primary hyperoxaluria #MMPMID25363903 Berini SE ; Tracy JA ; Engelstad JK ; Lorenz EC ; Milliner DS ; Dyck PJ Muscle Nerve 2015[Mar]; 51 (3 ): 449-54 PMID25363903 show ga INTRODUCTION: A 24-year-old man with primary hyperoxaluria type 1 (PH1) presented with a rapidly progressive axonal and demyelinating sensorimotor polyradiculoneuropathy shortly after the onset of end-stage renal disease. His plasma oxalate level was markedly elevated at 107 µmol/L (normal<1.8 µmol/L). METHODS: A sural nerve biopsy was performed. Teased fiber and paraffin and epoxy sections were done and morphometric procedures were performed on this sample and on an archived sample from a 22-year-old man as an age- and gender-matched control. Embedded teased fiber electron microscopy was also performed. RESULTS: The biopsy revealed secondary demyelination and axonal degeneration. Under polarized light, multiple bright hexagonal, rectangular, and starburst inclusions, typical of calcium oxalate monohydrate crystals, were seen. CONCLUSIONS: The proposed mechanisms of nerve damage include disruption of axonal transport due to crystal deposition, toxic effect of oxalate, or nerve ischemia related to vessel occlusion from oxalate crystal deposition. |*Disease Progression [MESH] |Calcium Oxalate/*metabolism [MESH] |Humans [MESH] |Hyperoxaluria, Primary/complications/diagnosis/*metabolism [MESH] |Male [MESH] |Polyradiculoneuropathy/diagnosis/etiology/*metabolism [MESH] |Sural Nerve/*metabolism/pathology [MESH]Progressive polyradiculoneuropathy due to intraneural oxalate depositi(epmc).pdf DeepDyve Pubget Overpricing